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KEL gene

Known as: CD238, KELL BLOOD GROUP GLYCOPROTEIN, KEL 
National Institutes of Health

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KEL GENE MUTATION ANALYSIS:PRID:PT:AMN:NAR:MOLGENKEL GENE MUTATION ANALYSIS:PRID:PT:AMN:NOM:MOLGENKell Blood-Group System

Papers overview

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2018
2018
Recipient priming to one RBC alloantigen directly enhances subsequent alloimmunization in mice.
Individuals that become immunized to red blood cell (RBC) alloantigens can experience an increased rate of antibody formation to… 
2016
2016
Antigen modulation as a potential mechanism of anti-KEL immunoprophylaxis in mice.
Red blood cell (RBC) alloimmunization is a serious complication of transfusion or pregnancy. Despite the widespread use of Rh… 
2011
2011
Identification of RHCE and KEL alleles in large cohorts of Afro‐Caribbean and Comorian donors by multiplex SNaPshot and fragment assays: a transfusion support for sickle cell disease patients
To lower the alloimmunization risk following transfusion in blacks, we developed two genotyping assays for large‐scale screening… 
2011
2011
Genetic and functional analyses describe a novel 730delG mutation in the KEL gene causing K0 phenotype in a Taiwanese blood donor
Aims/Objectives: The purpose of this study was to explore the molecular basis of the K0 phenotype of a Taiwanese blood donor… 
2006
2006
A KEL gene encoding serine at position 193 of the Kell glycoprotein results in expression of KEL1 antigen
BACKGROUND: The KEL2/KEL1 (k/K) blood group polymorphism represents 578C>T in the KEL gene and Thr193Met in the Kell glycoprotein… 
2002
2002
Heterozygosity for two novel null alleles of the KEL gene causes the Kell‐null phenotype in a Japanese woman
Summary.  The Kell‐null (Ko) phenotype is rare and it does not express the Kell antigens on erythrocyte membranes. Recently… 
2001
2001
Molecular Basis of the Kell-null Phenotype
The Kell blood group system is polymorphic, and 23 antigens have been defined to date. The Kell antigens are located on a single… 
Review
2000
Review
2000
The neprilysin family in health and disease.
The mammalian neprilysin (NEP) family comprises at least seven members: NEP itself, Kell blood group antigen (KELL), the… 
1999
1999
Identification of a defect in the intracellular trafficking of a Kell blood group variant.
Blood group polymorphisms have been used as tools to study the architecture of the red blood cell (RBC) membrane. Some blood… 
1987
1987
Diltiazem pharmacokinetics in the rat and relationship between its serum concentration and uterine and cardiovascular effects
1 The kinetics of diltiazem were investigated in ovariectomized (ovx) non‐pregnant and intact late pregnant anaesthetized rats… 
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