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KDM6B wt Allele

Known as: Jumonji D3, Jumonji Domain Containing 3, Histone Lysine Demethylase Gene, KIAA0346 
Human KDM6B wild-type allele is located in the vicinity of 17p13.1 and is approximately 15 kb in length. This allele, which encodes lysine-specific… 
National Institutes of Health

Related topics

Related topics

8 relations
17p13.1Cell Differentiation processDevelopmental processHomo sapiens

Papers overview

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2019
2019
Therapeutically targeting head and neck squamous cell carcinoma through synergistic inhibition of LSD1 and JMJD3 by TCP and GSK-J1
The histone demethylase LSD1 is a key mediator driving tumorigenesis, which holds potential as a promising therapeutic target… 
2017
2017
JMJD3 Is Crucial for the Female AVPV RIP-Cre Neuron-Controlled Kisspeptin–Estrogen Feedback Loop and Reproductive Function
The hypothalamic-pituitary-gonadal axis controls development, reproduction, and metabolism. Although most studies have focused on… 
2017
2017
Histone Methylation in Relation with Clinical Pathological Parameters in Prostate Cancer
DNA and histone methylation are both modifications closely link to stable repression. However, previous studies have shown that… 
2017
2017
[Distributions of H3K27me3 and its modification enzymes in different tissues of mice].
Objective To investigate the levels of trimethylated histone 3 at lysine residue 27 (H3K27me3) and its modification enzymes Zeste… 
2017
2017
Analyse transcriptomique d’un panel de gènes dans le cancer de la prostate et implication de la déméthylase JMJD3 et de la méthyltransférase EZH2
2016
2016
Rôle de l’histone méthyltransférase EZH2 et de la déméthylase JMJD3 dans les cancers de la prostate
2015
2015
Abstract 108: Inhibition of demethylase, JMJD3 sensitizes diffuse large B-cell lymphoma (DLBCL) to chemotherapy
Introduction Diffuse large B-cell lymphoma (DLBCL) is the most common form of non-Hodgkin9s lymphoma (NHL) representing more than… 
2012
2012
Configuration of a High-Content Imaging Platform for Hit Identification and Pharmacological Assessment of JMJD3 Demethylase Enzyme Inhibitors
The biological complexity associated with the regulation of histone demethylases makes it desirable to configure a cellular… 
2012
2012
[Effect of Jumonji domain-containing protein-3 on the proliferation and migration of lung cancer cell line].
For investigating the effect of Jumonji domain-containing protein-3 (JMJD3) on the behavior of lung cancer cell line, A549… 
2010
2010
Gene networking and canonical pathway analysis in a JMJD3 knockdown human monocytic cell line
JMJD3, a JmjC family histone demethylase, can be induced by the transcription factor NF‐kB in response to various stimuli. JMJD3… 
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