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KDM6B wt Allele

Known as: Jumonji D3, Jumonji Domain Containing 3, Histone Lysine Demethylase Gene, KIAA0346 
Human KDM6B wild-type allele is located in the vicinity of 17p13.1 and is approximately 15 kb in length. This allele, which encodes lysine-specific… Expand
National Institutes of Health

Papers overview

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2014
2014
Jumonji domain-containing proteins (JMJD) catalyze the oxidative demethylation of a methylated lysine residue of histones by… Expand
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Highly Cited
2012
Highly Cited
2012
The histone H3 Lys 27 (H3K27) demethylase JMJD3 has been shown to play important roles in transcriptional regulation and cell… Expand
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Highly Cited
2012
Highly Cited
2012
JMJD3 (KDM6B) antagonizes Polycomb silencing by demethylating lysine 27 on histone H3. The interplay of methyltransferases and… Expand
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Highly Cited
2012
Highly Cited
2012
Neural development requires crosstalk between signaling pathways and chromatin. In this study, we demonstrate that neurogenesis… Expand
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Highly Cited
2011
Highly Cited
2011
Chromatin represents a repressive barrier to the process of ligand-dependent transcriptional activity of nuclear receptors. Here… Expand
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Highly Cited
2011
Highly Cited
2011
KDM6B/JMJD3 is a histone H3 lysine demethylase with an important gene regulatory role in development and physiology. Here, we… Expand
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Highly Cited
2009
Highly Cited
2009
The INK4a/ARF tumor suppressor locus, a key executor of cellular senescence, is regulated by members of the Polycomb group (PcG… Expand
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Highly Cited
2008
Highly Cited
2008
The recent discovery of H3K27me3 demethylases suggests that H3K27me3 may dynamically regulate gene expression, but this potential… Expand
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Highly Cited
2007
Highly Cited
2007
The trithorax and the polycomb group proteins are chromatin modifiers, which play a key role in the epigenetic regulation of… Expand
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Highly Cited
2007
Highly Cited
2007
Histone methylation is an important epigenetic phenomenon that participates in a diverse array of cellular processes and has been… Expand
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