KDM6B wt Allele

Known as: Jumonji D3, Jumonji Domain Containing 3, Histone Lysine Demethylase Gene, KIAA0346 
Human KDM6B wild-type allele is located in the vicinity of 17p13.1 and is approximately 15 kb in length. This allele, which encodes lysine-specific… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2007-2017
05101520072017

Papers overview

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Highly Cited
2014
Highly Cited
2014
Pediatric brainstem gliomas often harbor oncogenic K27M mutation of histone H3.3. Here we show that GSKJ4 pharmacologic… (More)
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2012
2012
The histone H3 Lys 27 (H3K27) demethylase JMJD3 has been shown to play important roles in transcriptional regulation and cell… (More)
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2011
2011
The histone H3K27 demethylases UTX and JMJD3 are important regulatory factors that modulate gene expression by altering the… (More)
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2011
2011
KDM6B/JMJD3 is a histone H3 lysine demethylase with an important gene regulatory role in development and physiology. Here, we… (More)
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2011
2011
Chromatin represents a repressive barrier to the process of ligand-dependent transcriptional activity of nuclear receptors. Here… (More)
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Highly Cited
2009
Highly Cited
2009
The INK4a/ARF tumor suppressor locus, a key executor of cellular senescence, is regulated by members of the Polycomb group (PcG… (More)
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Highly Cited
2009
Highly Cited
2009
The tumor suppressor proteins p16INK4A and p14ARF, encoded by the INK4A-ARF locus, are key regulators of cellular senescence. The… (More)
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Highly Cited
2007
Highly Cited
2007
The trithorax and the polycomb group proteins are chromatin modifiers, which play a key role in the epigenetic regulation of… (More)
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Highly Cited
2007
Highly Cited
2007
Covalent modifications of histones, such as acetylation and methylation, play important roles in the regulation of gene… (More)
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Highly Cited
2007
Highly Cited
2007
Histone methylation is an important epigenetic phenomenon that participates in a diverse array of cellular processes and has been… (More)
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