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- Qinghua Wang, Romel Somwar, +4 authors Amira Klip
- Molecular and cellular biology
- 1999
L6 myoblasts stably transfected with a GLUT4 cDNA harboring an exofacial myc epitope tag (L6-GLUT4myc myoblasts) were used to study the role of protein kinase B alpha (PKBalpha)/Akt1 in the… (More)
- Elaine Xu, Mohan Kumar, +10 authors Qinghua Wang
- Cell metabolism
- 2006
Excessive secretion of glucagon is a major contributor to the development of diabetic hyperglycemia. Secretion of glucagon is regulated by various nutrients, with glucose being a primary determinant… (More)
- Qinghua Wang, PeterL. Young, Kylie J. Walters
- Journal of molecular biology
- 2005
Ubiquitin is a key regulatory molecule in diverse cellular events. How cells determine the outcome of ubiquitylation remains unclear; however, a likely determinant is the specificity of ubiquitin… (More)
- Qinghua Wang, Zeena Khayat, K. Kishi, Yousuke Ebina, Amira Klip
- FEBS letters
- 1998
We report a rapid and sensitive colorimetric approach to quantitate the amount of glucose transporters exposed at the surface of intact cells, using L6 muscle cells expressing GLUT4 containing an… (More)
- Valeria R. Fantin, Qinghua Wang, Gustav E. Lienhard, Susanna R Keller
- American journal of physiology. Endocrinology and…
- 2000
The insulin receptor substrates (IRSs) function in insulin signaling. Four members of the family, IRS-1 through IRS-4, are known. Previously, mice with targeted disruption of the genes for IRS-1, -2,… (More)
- Atsunori Ueyama, Karen Yaworsky, Qinghua Wang, Yousuke Ebina, Amira Klip
- American journal of physiology. Endocrinology and…
- 1999
Insulin stimulates glucose uptake into muscle and fat cells via recruitment of the glucose transporter 4 (GLUT-4) from intracellular store(s) to the cell surface. Robust stimulation of glucose uptake… (More)
- Kylie J. Walters, Patrycja J. Lech, Amanda M. Goh, Qinghua Wang, Peter M Howley
- Proceedings of the National Academy of Sciences…
- 2003
The Rad23 family of proteins, including the human homologs hHR23a and hHR23b, stimulates nucleotide excision repair and has been shown to provide a novel link between proteasome-mediated protein… (More)
- Qinghua Wang, Amanda M. Goh, Peter M Howley, Kylie J. Walters
- Biochemistry
- 2003
Ubiquitin is a prominent regulatory protein in numerous biological processes, including targeted protein degradation, endocytic sorting, transcriptional control, intranuclear localization, and… (More)
- Qinghua Wang, Kerry W S Ko, András Kapus, Christopher A McCulloch, Richard P. Ellen
- The Journal of biological chemistry
- 2001
The cytotoxicity of infectious agents can be mediated by disruption of calcium signaling in target cells. Outer membrane proteins of the spirochete Treponema denticola, a periodontal pathogen,… (More)
- Qinghua Wang, Xia Tian, Xiaorui Chen, Jianpeng Ma
- Proceedings of the National Academy of Sciences…
- 2007
Receptor-binding specificity of HA, the major surface glycoprotein of influenza virus, primarily determines the host ranges that the virus can infect. Influenza type B virus almost exclusively… (More)