KDM6A wt Allele

Known as: UTX, Ubiquitously Transcribed Tetratricopeptide Repeat, X Chromosome Gene, MGC141941 
Human KDM6A wild-type allele is located in the vicinity of Xp11.2 and is approximately 238 kb in length. This allele, which encodes lysine-specific… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive form of leukemia that is mainly diagnosed in children and shows a… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Review
2014
Review
2014
In 2007, the Ubiquitously Transcribed Tetratricopeptide Repeat on chromosome X (UTX) was identified as a histone demethylase that… (More)
  • figure 1
Is this relevant?
Highly Cited
2014
Highly Cited
2014
Histone methyltransferases and demethylases reversibly modulate histone lysine methylation, which is considered a key epigenetic… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Chronic myelomonocytic leukemia (CMML), a myelodysplastic/myeloproliferative neoplasm, is characterized by monocytic… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Tri- and dimethylations of histone H3K9 (H3K9me3/2) and H3K27 (H3K27me3/2), both situated in the "A-R-Kme-S" sequence motif… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
2010
2010
The epigenetic marks H3K27me3 and H3K4me3 are important repressive and permissive histone modifications, respectively, which are… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Somatically acquired epigenetic changes are present in many cancers. Epigenetic regulation is maintained via post-translational… (More)
Is this relevant?
Highly Cited
2007
Highly Cited
2007
The recent discovery of a large number of histone demethylases suggests a central role for these enzymes in regulating histone… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2007
Highly Cited
2007
The trithorax and the polycomb group proteins are chromatin modifiers, which play a key role in the epigenetic regulation of… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1998
Highly Cited
1998
We recently have identified a ubiquitously transcribed mouse Y chromosome gene, Uty , which encodes a tetratricopeptide repeat… (More)
  • figure 1
  • figure 3
  • figure 2
  • figure 4
  • table 1
Is this relevant?