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KCNQ4 gene

Known as: POTASSIUM CHANNEL, VOLTAGE-GATED, KQT-LIKE SUBFAMILY, MEMBER 4, potassium voltage-gated channel subfamily Q member 4, POTASSIUM CHANNEL, VOLTAGE-GATED, SUBFAMILY Q, MEMBER 4 
National Institutes of Health

Papers overview

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2019
2019
A mutually induced conformational fit underlies Ca2+-directed interactions between calmodulin and the proximal C terminus of KCNQ4 K+ channels
Calmodulin (CaM) conveys intracellular Ca2+ signals to KCNQ (Kv7, “M-type”) K+ channels and many other ion channels. Whether this… 
2014
2014
A Japanese family showing high-frequency hearing loss with KCNQ4 and TECTA mutations
Abstract Conclusions: We describe a Japanese family with high-frequency sensorineural hearing loss (SNHL) harboring a c.211delC… 
2013
2013
Downregulation of KCNQ4 by Janus Kinase 2
Janus kinase-2 (JAK2) participates in the signaling of several hormones, growth factors and cytokines. Further stimulators of… 
2013
2013
Moderate hearing loss associated with a novel KCNQ4 non-truncating mutation located near the N-terminus of the pore helix.
2011
2011
Identification of novel KCNQ4 openers by a high-throughput fluorescence-based thallium flux assay.
2010
2010
Aminoglycosides Inhibit KCNQ 4 Channels in Cochlear Outer Hair Cells via Depletion of Phosphatidylinositol ( 4 , 5 ) bisphosphate
Aminoglycoside antibiotics (AGs) are severely ototoxic. AGs cause degeneration of outer hair cells (OHCs), leading to profound… 
2007
2007
Thyroid hormone receptor alpha1 is a critical regulator for the expression of ion channels during final differentiation of outer hair cells.
Cochlear outer hair cells (OHCs) terminally differentiate prior to the onset of hearing. During this time period, thyroid hormone… 
2006
2006
Studies of the effect of ionomycin on the KCNQ4 channel expressed in Xenopus oocytes.
Highly Cited
2005
Highly Cited
2005
Regulation of the voltage-gated potassium channel KCNQ4 in the auditory pathway
The potassium channel KCNQ4, expressed in the mammalian cochlea, has been associated tentatively with an outer hair cell (OHC… 
2003
2003
Voltage-independent KCNQ4 currents induced by (±)BMS-204352
AbstractThe compound BMS-204352 has been targeted for use against acute ischemic stroke, due to its activation of the large… 
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