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KCNH2 gene

Known as: POTASSIUM CHANNEL, VOLTAGE-GATED, SUBFAMILY H, MEMBER 2, Kv11.1, ETHER-A-GO-GO-RELATED GENE, HUMAN 
National Institutes of Health

Related topics

Related topics

2 relations
ERG1 Potassium ChannelKCNV2 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Shape signatures: new descriptors for predicting cardiotoxicity in silico.
Shape Signatures is a new computational tool that is being evaluated for applications in computational toxicology and drug… 
Highly Cited
2005
Highly Cited
2005
HERG-Lite: a novel comprehensive high-throughput screen for drug-induced hERG risk.
Review
2004
Review
2004
Adrenergic regulation of the rapid component of the cardiac delayed rectifier potassium current, IKr, and the underlying hERG ion channel
Abstract.Ventricular arrhythmias are often precipitated by physical or emotional stress, in particular in patients with ischemic… 
Highly Cited
2003
Highly Cited
2003
Regulation of HERG potassium channel activation by protein kinase C independent of direct phosphorylation of the channel protein.
Highly Cited
2002
Highly Cited
2002
Association between HERG K897T polymorphism and QT interval in middle-aged Finnish women.
Highly Cited
2002
Highly Cited
2002
Interaction with GM130 during HERG Ion Channel Trafficking
Many mutations in the Human Ether-à-go-go-Related Gene (HERG) cause type 2 congenital long QT syndrome (LQT2) by disrupting… 
Highly Cited
2001
Highly Cited
2001
Analysis of the Cyclic Nucleotide Binding Domain of the HERG Potassium Channel and Interactions with KCNE2*
Mutations in the cyclic nucleotide binding domain (CNBD) of the human ether-a-go-go-related gene (HERG) K+ channel are associated… 
Review
2000
Review
2000
Survey of the coding region of the HERG gene in long QT syndrome reveals six novel mutations and an amino acid polymorphism with possible phenotypic effects
Analysis of the entire coding region of the HERG gene of 39 Finnish LQTS patients revealed eight mutations, six of which are… 
Highly Cited
1999
Highly Cited
1999
N‐linked glycosylation sites determine HERG channel surface membrane expression
1 Long QT syndrome (LQT) is an electrophysiological disorder that can lead to sudden death from cardiac arrhythmias. One form of… 
Review
1999
Review
1999
A plethora of mechanisms in the HERG-related long QT syndrome. Genetics meets electrophysiology.
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