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KB 5246

Known as: 3H,8H-4-Oxa-1-thia-9b-azacyclopenta(cd)phenalene-9-carboxylic acid, 6-fluoro-5-(4-methyl-1-piperazinyl)-8-oxo-, monohydrochloride, KB-5246 
National Institutes of Health

Related topics

Related topics

3 relations
KB Cells

Broader (2)

PhenalenesQuinolones

Papers overview

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Review
1992
Review
1992
In vitro properties of the newer quinolones.
Table 5 summarizes the activity of the newer quinolones against various bacteria including intracellular bacteria and the other… 
1992
1992
Lack of effect of carbonyl cyanide m-chlorophenylhydrazone on KB-5246 accumulation by Staphylococcus aureus
The accumulation of KB-5246 in a quinolone-susceptible strain of Staphylococcus aureus was about 70 times that of norfloxacin… 
1990
1990
Activity of KB-5246 against outer membrane mutants of Escherichia coli and Salmonella typhimurium
The inhibitory activity of KB-5246 against Escherichia coli DNA gyrase and the antibacterial activity and apparent uptake in E… 
1990
1990
Structure-activity relationship of quinolone antibacterial agents: the effects of C-2 substitution.
Very little is known about the structure-activity relationship of quinolone antibacterials at the 2-position. Because of the loss… 
1989
1989
In vitro and in vivo antibacterial activities of KB-5246, a new tetracyclic quinolone
The in vitro and in vivo antibacterial activities of KB-5246, a tetracyclic quinolone, were compared with those of ciprofloxacin… 
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