Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

KAT8 wt Allele

Known as: MYST1, FLJ14040, PP7073 
Human KAT8 wt allele is located in the vicinity of 16p11.2 and is approximately 14 kb in length. This allele, which encodes histone acetyltransferase… Expand
National Institutes of Health

Related topics

Related topics

3 relations
CREBBP protein, humanKAT7 protein, human

Broader (1)

KAT8 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Myocardin-related transcription factor A (MRTF-A) contributes to acute kidney injury by regulating macrophage ROS production.
  • L. Liu, X. Wu, +6 authors Y. Xu
  • Biochimica et biophysica acta. Molecular basis of…
  • 2018
    • Corpus ID: 49268813
A host of pathogenic factors induce acute kidney injury (AKI) leading to insufficiencies of renal function. In the present study… Expand
2016
2016
The characterisation of LATS2 kinase regulation in Hippo-YAP signalling.
By controlling the YAP1 proto-oncoprotein Hippo signalling plays important roles in cancer-associated processes. Current evidence… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Highly Cited
2014
Highly Cited
2014
The histone acetylranseferase hMOF acetylates Nrf2 and regulates anti‐drug responses in human non‐small cell lung cancer
The histone acetyltransferase MOF is a member of the MYST family. In mammals, MOF plays critical roles by acetylating histone H4… Expand
2014
2014
Correlation of low expression of hMOF with clinicopathological features of colorectal carcinoma, gastric cancer and renal cell carcinoma.
Human MOF (males absent on the first), as a histone acetyltransferase, is responsible for histone H4K16 acetylation in human… Expand
  • figure 1
  • figure 2
  • figure 3
  • table I
  • figure 4
2013
2013
Epigenetic change in kidney tumor: downregulation of histone acetyltransferase MYST1 in human renal cell carcinoma
BackgroundMYST1 (also known as hMOF), a member of the MYST family of histone acetyltransferases (HATs) as an epigenetic mark of… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
2013
2013
Histone acetyltransferase hMOF promotes S phase entry and tumorigenesis in lung cancer.
hMOF is the major acetyltransferase of histone H4 lysine 16 (H4K16) in humans, but its biological function is not well understood… Expand
  • table 1
  • table 2
  • figure 1
  • figure 2
  • figure 3
2013
2013
Crosstalk between NSL Histone Acetyltransferase and MLL/SET Complexes: NSL Complex Functions in Promoting Histone H3K4 Di-Methylation Activity by MLL/SET Complexes
hMOF (MYST1), a histone acetyltransferase (HAT), forms at least two distinct multiprotein complexes in human cells. The male… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Highly Cited
2011
Highly Cited
2011
SUV420H2-Mediated H4K20 Trimethylation Enforces RNA Polymerase II Promoter-Proximal Pausing by Blocking hMOF-Dependent H4K16 Acetylation
ABSTRACT Many human genes exhibit evidence of initiated RNA polymerase II (Pol II) at their promoters, despite a lack of… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Highly Cited
2010
Highly Cited
2010
Opposing effects of hMOF and SIRT1 on H4K16 acetylation and the sensitivity to the topoisomerase II inhibitor etoposide
Various inhibitors of histone deacetylase (HDAC) activity can sensitize drug resistant cancer cells to chemotherapeutic agents… Expand
  • figure 2
  • figure 4
  • figure 6
Highly Cited
2008
Highly Cited
2008
Role of hMOF-dependent histone H4 lysine 16 acetylation in the maintenance of TMS1/ASC gene activity.
Epigenetic silencing of tumor suppressor genes in human cancers is associated with aberrant methylation of promoter region CpG… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE