Juvenile psoriatic arthritis

Background  Alterations in specific signal transduction pathways may explain the hyperproliferation and abnormal differentiation… Expand

Keratinocytes (KC) are important source of and targets for several cytokines. Although KC express IL-15 mRNA, the functional… Expand

BACKGROUND The genetic and immunological basis for psoriasis is unknown. Through the use of a severe combined immunodeficient… Expand

In epidermis, it has been suggested, intercellular communication through gap junctions is important in coordinating cell behavior… Expand

The expression of mRNA encoding peroxisome proliferator-activated receptor (PPAR) subtypes in human keratinocytes was determined… Expand

Telomeres are the end regions of linear chromosomes, and in normal somatic cells the lengths of telomeres shorten with successive… Expand

Keratinocyte differentiation in psoriasis was examined using a panel of monospecific monoclonal antibodies to keratins (K… Expand

Psoriasis is a common inherited skin disease that is characterized by hyperproliferation of epidermal keratinocytes and excessive… Expand

A proposed definition of juvenile psoriatic arthritis (JPsA) was used to identify definite or probable JPsA in 35 children… Expand

Ro 10-9359 is a retinoic acid derivative, selected for study because of a better tolerance than retinoic acid, shown in animal… Expand