JSM6427
National Institutes of Health
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
OBJECTIVE
To evaluate the pharmacologic activity and tolerability of JSM6427, a potent and first selective small-molecule…
As researchers and clinicians are beginning to understand that wet age-related macular degeneration (AMD) is more than simply a…
PURPOSE
The aim of this study was to determine the expression and localization of integrin alpha5beta1 in human retinal pigment…
Objective : To evaluate the pharmacologic activity and tolerability of JSM6427, a potent and first selective small-molecule…
JSM6427 is a highly potent and specific small molecule alpha(5)beta(1) integrin antagonist. JSM6427 blockade of alpha(5)beta(1…
PURPOSE
Integrin alpha5beta1, a fibronectin receptor, is involved in endothelial cell migration and proliferation. Here we…
Integrin α5β1 plays an important role in developmental angiogenesis, but its role in various types of pathologic…
Integrin alpha(5)beta(1) plays an important role in developmental angiogenesis, but its role in various types of pathologic…