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JSM6427

National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
OBJECTIVE To evaluate the pharmacologic activity and tolerability of JSM6427, a potent and first selective small-molecule… 
Review
2009
Review
2009
As researchers and clinicians are beginning to understand that wet age-related macular degeneration (AMD) is more than simply a… 
2009
2009
PURPOSE The aim of this study was to determine the expression and localization of integrin alpha5beta1 in human retinal pigment… 
2009
2009
Methods: JSM6427 selectivity for 5 1 was evaluated by in vitro binding assays while the ability of JSM6427 to inhibit CNV was… 
2008
2008
2008
2008
JSM6427 is a highly potent and specific small molecule alpha(5)beta(1) integrin antagonist. JSM6427 blockade of alpha(5)beta(1… 
2007
2007
PURPOSE Integrin alpha5beta1, a fibronectin receptor, is involved in endothelial cell migration and proliferation. Here we… 
Highly Cited
2006
Highly Cited
2006
Integrin α5β1 plays an important role in developmental angiogenesis, but its role in various types of pathologic… 
2006
2006
Integrin alpha(5)beta(1) plays an important role in developmental angiogenesis, but its role in various types of pathologic…