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JSM6427

National Institutes of Health

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3 relations

Broader (3)

PropionatesPyridinesPyrrolidines

Papers overview

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Highly Cited
2009
Highly Cited
2009
Preclinical evaluation of the novel small-molecule integrin alpha5beta1 inhibitor JSM6427 in monkey and rabbit models of choroidal neovascularization.
OBJECTIVE To evaluate the pharmacologic activity and tolerability of JSM6427, a potent and first selective small-molecule… 
2009
2009
Integrin alpha5beta1 mediates attachment, migration, and proliferation in human retinal pigment epithelium: relevance for proliferative retinal disease.
PURPOSE The aim of this study was to determine the expression and localization of integrin alpha5beta1 in human retinal pigment… 
2009
2009
Preclinical Evaluation of the Novel Small-Molecule Integrin (cid:2) 5 (cid:3) 1 Inhibitor JSM6427 in Monkey and Rabbit Models of Choroidal Neovascularization
Objective : To evaluate the pharmacologic activity and tolerability of JSM6427, a potent and first selective small-molecule… 
2008
2008
JSM6427, a Small Molecule alpha(5)beta(1) Integrin Inhibitor
JSM6427 is a highly potent and specific small molecule alpha(5)beta(1) integrin antagonist. JSM6427 blockade of alpha(5)beta(1… 
2008
2008
Integrin 5β1 Specific Antagonist JSM6427 Inhibits Human RPE Cell Attachment, Migration, and Proliferation
2007
2007
Modulation of hypoxia-induced neovascularization by JSM6427, an integrin alpha5beta1 inhibiting molecule.
PURPOSE Integrin alpha5beta1, a fibronectin receptor, is involved in endothelial cell migration and proliferation. Here we… 
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