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JP-1302

National Institutes of Health

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2 relations

Broader (2)

AcridinesPiperazines

Papers overview

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2018
2018
Inhibition of &agr;2C‐adrenoceptors ameliorates cisplatin‐induced acute renal failure in rats
2018
2018
Post-treatment with JP-1302 protects against renal ischemia/reperfusion-induced acute kidney injury in rats.
2015
2015
Specific Role of α2A‐ and α2B‐, but not α2C‐, Adrenoceptor Subtypes in the Inhibition of the Vasopressor Sympathetic Out‐flow in Diabetic Pithed Rats
Several lines of evidence have shown an association of diabetes with a catecholamines' aberrant homeostasis involving a drastic… 
2013
2013
The α2-adrenoceptors mediating inhibition of the vasopressor sympathetic outflow in pithed rats: pharmacological correlation with α2A, α2B and α2C subtypes.
2013
2013
Role of α2-adrenoceptors in Electrical Field Stimulation–induced Contraction of Pig Nasal Mucosa and Pharmacologic Characterization of a Novel α2C-adrenoceptor Agonist
Background Blood vessels of the nasal mucosa are richly innervated by sympathetic nerves and neural mechanism is of great… 
2012
2012
Pharmacological identification of the α₂-adrenoceptor subtypes mediating the vasopressor responses to B-HT 933 in pithed rats.
2012
2012
α2C-Adrenoceptors modulate L-DOPA uptake in opossum kidney cells and in the mouse kidney.
Targeted deletion or selective pharmacological inhibition of α(2C)-adrenoceptors in mice results in increased brain tissue levels… 
2010
2010
Activation of Spinal &agr;-2 Adrenoceptors, but Not &mgr;-Opioid Receptors, Reduces the Intrathecal N-Methyl-d-Aspartate-Induced Increase in Spinal NR1 Subunit Phosphorylation and Nociceptive…
BACKGROUND: A previous study from our laboratories showed that a significant reduction in spinal N-methyl-d-aspartate (NMDA… 
2010
2010
Alpha-2c-Adrenergic Receptors Contribute to Basal Nasal Patency in the Anesthetized Cat
Background: Nasal congestion is the most troublesome symptom associated with a variety of upper airway diseases, including… 
2007
2007
JP-1302: a new tool to shed light on the roles of alpha2C-adrenoceptors in brain.
The discovery of JP-1302 as a selective, high affinity antagonist at the alpha2C-adrenoceptor will enable researchers to probe… 
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