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JP-1302

 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Ischemia/reperfusion injury is the most common cause of acute kidney injury. We previously revealed that pre-treatment with… Expand
2016
2016
Excitation of renal sympathetic nervous activity and the resulting increased levels of renal venous norepinephrine play important… Expand
2013
2013
The α2‐adrenoceptors (ARs) are important modulators of a wide array of physiological responses. As only a few selective compounds… Expand
2013
2013
α2-Adrenoceptors were first described as presynaptic receptors inhibiting the release of various transmitters from neurons in the… Expand
2010
2010
BACKGROUND: A previous study from our laboratories showed that a significant reduction in spinal N-methyl-d-aspartate (NMDA… Expand
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2009
2009
We examined the effects of JP-1302 (a selective alpha2C antagonist), BRL-44408 (a selective alpha2A antagonist) and yohimbine (a… Expand
Highly Cited
2008
Highly Cited
2008
Dexmedetomidine is a highly specific, potent and selective α2‐adrenoceptor agonist. Although intrathecal and epidural… Expand
2008
2008
Indirect experimental evidence suggests that drugs acting on the α2C‐adrenoceptor could be useful in the treatment of… Expand
Highly Cited
2007
Highly Cited
2007
Pharmacological validation of novel functions for the α2A‐, α2B‐, and α2C‐adrenoceptor (AR) subtypes has been hampered by the… Expand
2007
2007
The discovery of JP-1302 as a selective, high affinity antagonist at the alpha2C-adrenoceptor will enable researchers to probe… Expand