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JNJ16259685

National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Preclinical anaylses of [18F]cEFQ as a PET tracer for imaging metabotropic glutamate receptor type 1 (mGluR1)
Metabotropic glutamate receptor type 1 (mGluR1) is related with various neurological and psychiatric diseases, such as anxiety… 
2014
2014
Metabotropic glutamate receptors regulate cortical gamma hyperactivities elicited by ketamine in rats
2014
2014
Properties of 4 Hz stimulation‐induced parallel fiber–Purkinje cell presynaptic long‐term plasticity in mouse cerebellar cortex in vivo
Cerebellar parallel fiber–Purkinje cell (PF–PC) long‐term synaptic plasticity is important for the formation and stability of… 
2014
2014
Estudio de la instigación social en un modelo de agresión inducida por aislamiento: efectos de la administración de JNJ16259685, un antagonista de receptores mGlu1
La instigacion social intensifica la conducta agresiva permitiendo observar niveles mas extremos de agresion. Estudios recientes… 
Highly Cited
2012
Highly Cited
2012
Subregion‐specific role of glutamate receptors in the nucleus accumbens on drug context‐induced reinstatement of cocaine‐seeking behavior in rats
The functional integrity of the nucleus accumbens (NAC) core and shell is necessary for contextual cocaine‐seeking behavior in… 
2012
2012
Synthesis, radiolabelling and in vitro and in vivo evaluation of a novel fluorinated ABP688 derivative for the PET imaging of metabotropic glutamate receptor subtype 5.
(E)-3-(Pyridin-2-ylethynyl)cyclohex-2-enone O-(2-(3-(18)F-fluoropropoxy)ethyl) oxime ([(18)F]-PSS223) was evaluated in vitro and… 
2011
2011
Characterization of the selective mGluR1 antagonist, JNJ16259685, in rodent models of movement and coordination
2008
2008
Increased efficacy of μ-opioid agonist-induced antinociception by metabotropic glutamate receptor antagonists in C57BL/6 mice: comparison with (−)-6-phosphonomethyl-deca-hydroisoquinoline-3…
RationaleRecent experimental data suggest that metabotropic glutamate receptor (mGluR) antagonists with selectivity for mGluR1… 
2008
2008
Morphine in Combination with Metabotropic Glutamate Receptor Antagonists on Schedule-Controlled Responding and Thermal Nociception
The present study examined the interactive effects of morphine in combination with metabotropic glutamate (mGlu) receptor… 
2007
2007
Potent and specific action of the mGlu1 antagonists YM‐298198 and JNJ16259685 on synaptic transmission in rat cerebellar slices
Specific and selective inhibitors for mGlu1 receptors are presently inadequate. A new generation of non‐competitive mGlu1… 
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