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JD5037

Known as: JD-5037 
 
National Institutes of Health

Papers overview

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2020
2020
BACKGROUND AND PURPOSE Liver fibrosis is a serious cause of morbidity and mortality worldwide and has no adequate treatment… Expand
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2019
2019
Endocannabinoids acting on the cannabinoid-1 receptor (CB1R) or ghrelin acting on its receptor (GHS-R1A) both promote alcohol… Expand
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2019
2019
Endocannabinoids promote energy conservation in obesity, whereas cannabinoid-1 receptor (CB1 R) blockade reverses body weight… Expand
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2017
2017
Objective In visceral obesity, an overactive endocannabinoid/CB1 receptor (CB1R) system promotes increased caloric intake and… Expand
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2017
2017
Abstract Cannabinoid receptor 1 (CB1R) antagonists have been proven to be effective anti‐obesity drugs; however, psychiatric side… Expand
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2017
2017
JD5037 (1) is a potent and selective, peripherally acting inverse agonist of the cannabinoid (CB1 R) receptor. Peripheral CB1… Expand
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Review
2017
Review
2017
Despite the enormous public health problem caused by obesity and its metabolic complications, available treatments are limited… Expand
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2016
2016
Therapeutics aimed at blocking the cannabinoid 1 (CB1) receptor for treatment of obesity resulted in significant improvements in… Expand
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Highly Cited
2015
Highly Cited
2015
UNLABELLED Hepatocellular carcinoma (HCC) has high mortality and no adequate treatment. Endocannabinoids interact with hepatic… Expand
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Highly Cited
2014
Highly Cited
2014
UNLABELLED Obesity is associated with increased activity of two lipid signaling systems (endocannabinoids [ECs] and ceramides… Expand
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