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J 111225

Known as: J 111,225, J-111,225, J-111225 
National Institutes of Health

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Broader (1)

Carbapenems

Papers overview

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2001
2001
Practical synthesis of a 1beta-methylcarbapenem, J-111,225, using 4-mercapto-2-[4-(N-methylaminomethyl)phenyl]pyrrolidine as a precursor.
An effective and practical procedure for the synthesis of J-111,225 (1), a new 1beta-methylcarbapenem, was developed using 4… 
2000
2000
Therapeutic efficacy of J-111,225, a novel trans-3,5-disubstituted pyrrolidinylthio-1beta-methylcarbapenem, against experimental murine systemic infections.
In a murine model of systemic infection with methicillin-resistant Staphylococcus aureus (MRSA), J-111,225 showed an ED(50) value… 
2000
2000
Discovery of novel trans-3,5-disubstituted pyrrolidinylthio-1beta-methylcarbapenems.
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