Isochores

Known as: Isochore, Isochores [Chemical/Ingredient] 
Large regions of the GENOME that contain local similarities in BASE COMPOSITION.
National Institutes of Health

Papers overview

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2008
2008
Chromosome replication timing is biphasic (early-late) in the cell cycle of vertebrates and of most (possibly all) eukaryotes. In… (More)
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Highly Cited
2003
Highly Cited
2003
The housekeeping (ubiquitously expressed) genes in the mammal genome were shown here to be on average slightly GC-richer than… (More)
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Review
2003
Review
2003
The mouse Fxy gene was translocated into the highly recombining pseudoautosomal region comparatively recently in evolutionary… (More)
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Highly Cited
2002
Highly Cited
2002
To understand the origin and evolution of isochores-the peculiar spatial distribution of GC content within mammalian genomes-we… (More)
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Highly Cited
2001
Highly Cited
2001
In an attempt to understand the origin of CpG islands (CGIs) in mammalian genomes, we have studied their location and structure… (More)
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Highly Cited
2000
Highly Cited
2000
DNA melting is rate-limiting for cytosine deamination, from which we infer that the rate of cytosine deamination should decline… (More)
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Highly Cited
1999
Highly Cited
1999
It has been suggested that mutation bias is the major determinant of base composition bias at synonymous, intron, and flanking… (More)
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Highly Cited
1995
Highly Cited
1995
We compared the exon/intron organization of vertebrate genes belonging to different isochore classes, as predicted by their GC… (More)
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Review
1993
Review
1993
Vertebrate genomes are mosaics of isochores--namely, of long (> 300 kb), compositionally homogeneous DNA segments that can be… (More)
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Highly Cited
1985
Highly Cited
1985
Most of the nuclear genome of warm-blooded vertebrates is a mosaic of very long (much greater than 200 kilobases) DNA segments… (More)
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