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Iodine I 124 PU-AD

Known as: 124I-PU-AD, [124I]-PU-AD 
A radioconjugate composed of PU-AD, a synthetic purine-scaffold inhibitor of the molecular chaperone heat shock protein 90 (Hsp90), conjugated to the… 
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Mechanisms of Glucose Homeostasis After Roux-en-Y Gastric Bypass Surgery in the Obese, Insulin-Resistant Zucker Rat
Objective:Obesity-related diabetes is caused by insulin resistance and β-cell dysfunction. The current study examines changes in… 
Highly Cited
2009
Highly Cited
2009
The Role of Nanoparticle Layer Separation in the Finite Deformation Response of Layered Polyurethane-Clay Nanocomposites
Nanoscale control of structure in polymer nanocomposites is critical for their performance but has been difficult to investigate… 
Highly Cited
2003
Highly Cited
2003
Selective I kappa B kinase expression in airway epithelium generates neutrophilic lung inflammation.
To determine whether NF-kappaB activation is sufficient to generate lung inflammation in vivo, we selectively expressed a… 
Highly Cited
1998
Highly Cited
1998
Diet restriction increases apoptosis in the gut of aging rats.
Previous studies have shown that epithelial cell production rates are increased throughout the gastrointestinal tract in aging… 
Highly Cited
1996
Highly Cited
1996
Caloric restriction increases the expression of heat shock protein in the gut.
OBJECTIVE The authors determined whether caloric restriction (CR) either acutely or chronically, alters heat shock protein 70… 
Highly Cited
1995
Highly Cited
1995
Dietary lipids and calorie restriction affect mammary tumor incidence and gene expression in mouse mammary tumor virus/v-Ha-ras transgenic mice.
We have studied the effects of food restriction (FR) and substitution of fish oil (FO; omega 3) for corn oil (CO; omega 6) on… 
Highly Cited
1994
Highly Cited
1994
The Effects of Overfeeding and Dietary Restriction on Sprague-Dawley Rat Survival and Early Pathology Biomarkers of Aging
A significant correlation exists between average daily food consumption and 2-yr survival in control ad libitum (AL)–fed Sprague… 
Highly Cited
1984
Highly Cited
1984
Effects of level of feed intake on nitrogen, amino acid and energy digestibilities measured at the end of the small intestine and over the total digestive tract of growing pigs.
A replicated trial of 3 X 3 Latin square design was conducted with growing pigs (about 29 kg initially) to determine the effects… 
Highly Cited
1963
Highly Cited
1963
The Zw Blood Group System in Platelets
A new specific platelet antigen is described, detected by means of an agglutinin, present in the serum of a multiply transfused… 
Highly Cited
1946
Highly Cited
1946
Clinical method for the chromatographic-colorimetric determination of urinary 17-ketosteroids.
DURING recent years determinations of the 17-ketosteroid content of urine have been made in addition to or instead of the… 
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