Iodine I 124 PU-AD

Known as: 124I-PU-AD, [124I]-PU-AD 
A radioconjugate composed of PU-AD, a synthetic purine-scaffold inhibitor of the molecular chaperone heat shock protein 90 (Hsp90), conjugated to the… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
While diet-induced obesity has been exclusively attributed to increased caloric intake from fat, animals fed a high-fat diet (HFD… (More)
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Highly Cited
2008
Highly Cited
2008
Alzheimer's disease constitutes a rising threat to public health. Despite extensive research in cellular and animal models… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Glioblastoma multiforme (GBM) is the most aggressive primary brain tumor that carries a 5-y survival rate of 5… (More)
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Highly Cited
2006
Highly Cited
2006
Reduced intake of nutrients [calorie restriction (CR)] extends longevity in organisms ranging from yeast to mammals. Mutations… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Dysregulation of adipocyte-derived bioactive molecules plays an important role in the development of atherosclerosis… (More)
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Highly Cited
2000
Highly Cited
2000
LGMD1B is an autosomal dominantly inherited, slowly progressive limb girdle muscular dystrophy, with age-related atrioventricular… (More)
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Highly Cited
2000
Highly Cited
2000
Congestion and flow control is an integral part of any Interne t data transport protocol. It is widely accepted that the… (More)
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Highly Cited
1999
Highly Cited
1999
The collaborative Interagency Agreement between the National Center for Toxicological Research (NCTR) and the National Institute… (More)
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Highly Cited
1995
Highly Cited
1995
Recent extinction rates are 100 to 1000 times their pre-human levels in well-known, but taxonomically diverse groups from widely… (More)
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Highly Cited
1995
Highly Cited
1995
Apolipoprotein E (apoE) is critical in the modulation of cholesterol and phospholipid transport between cells of different types… (More)
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