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Intrinsic factor

Known as: Factor, Intrinsic, Intrinsic Factor [Chemical/Ingredient], factor intrinsic 
A glycoprotein secreted by the cells of the GASTRIC GLANDS that is required for the absorption of VITAMIN B 12 (cyanocobalamin). Deficiency of… 
National Institutes of Health

Related topics

Related topics

27 relations
Anemia, MegaloblasticAnemia, PerniciousCoagulation factor.intrinsic factor:Imp:Pt:PPP:NarGIF gene

Broader (3)

Gastric Juice (substance)GlycoproteinsMucoproteins

Narrower (2)

Intrinsic Factor Deficiencytrinsicon

Papers overview

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Highly Cited
1999
Highly Cited
1999
Molecular dynamics simulations of solvated yeast tRNA(Asp).
Highly Cited
1997
Highly Cited
1997
Effective size and F-statistics of subdivided populations. I. Monoecious species with partial selfing.
Assuming discrete generations and autosomal inheritance involving genes that do not affect viability or reproductive ability, we… 
Highly Cited
1995
Highly Cited
1995
Inhibition of the intrinsic factor X activating complex by protein S: evidence for a specific binding of protein S to factor VIII.
Protein S is a vitamin K-dependent nonenzymatic anticoagulant protein that acts as a cofactor to activated protein C. Recently it… 
Highly Cited
1989
Highly Cited
1989
Structure of the cDNA encoding transcobalamin I, a neutrophil granule protein.
Highly Cited
1979
Highly Cited
1979
Respective influence of extrinsic and intrinsic factors on the age-related decrease of thymic secretion.
The serum level of a circulating thymic factor (FTS) described in our laboratory diminishes in mice after adult thymectomy and… 
Highly Cited
1973
Highly Cited
1973
Isolation of gastric vitamin B 12 -binding proteins using affinity chromatography. I. Purification and properties of human intrinsic factor.
Abstract Human intrinsic factor has been isolated from gastric juice. The protein was purified 853-fold with a yield of 85… 
Review
1970
Review
1970
Absorption and malabsorption of vitamin B 12.
Highly Cited
1966
Highly Cited
1966
Occurrence in gastric juice of antibody to a complex of intrinsic factor and vitamin B12.
ANTIBODIES to gastric parietal cells have been found by an immunofluorescent technic in the gastric juice of patients with… 
Highly Cited
1962
Highly Cited
1962
Antibody to intrinsic factor in serum from patients with pernicious anemia.
Schwartz (1, 2) and Taylor (3) have suggested that sera from patients with pernicious anemia may contain antibody to intrinsic… 
Highly Cited
1953
Highly Cited
1953
Development of knowledge concerning the gastric intrinsic factor and its relation to pernicious anemia.
THOMAS ADDISON,1 physician to Guy's Hospital, London, published his classic description of pernicious anemia in 1855. Since then… 
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