Interferon beta-1a

Known as: Interferon.beta 1a, beta 1a, Interferon, IFN-beta 
An interferon beta-1 subtype that has a methionine at position 1, a cysteine at position 17, and is glycosylated at position 80. It functions as an… (More)
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
BACKGROUND B cells influence the pathogenesis of multiple sclerosis. Ocrelizumab is a humanized monoclonal antibody that… (More)
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Highly Cited
2015
Highly Cited
2015
BACKGROUND Daclizumab high-yield process (HYP) is a humanized monoclonal antibody that binds to CD25 (alpha subunit of the… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND The anti-CD52 monoclonal antibody alemtuzumab reduced disease activity in a phase 2 trial of previously untreated… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Fingolimod (FTY720), a sphingosine-1-phosphate-receptor modulator that prevents lymphocyte egress from lymph nodes… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Alemtuzumab, a humanized monoclonal antibody that targets CD52 on lymphocytes and monocytes, may be an effective… (More)
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE To conduct systematic long-term follow-up (LTFU) of patients in the Prevention of Relapses and Disability by Interferon… (More)
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Highly Cited
2005
Highly Cited
2005
Viral infection or stimulation of TLR3 triggers signaling cascades, leading to activation of the transcription factors IRF-3 and… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Interferon beta (IFNbeta) reduces relapses and MRI activity in relapsing-remitting MS (RRMS), with variable effects on… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Treatment with interferon beta has been shown to help patients with established multiple sclerosis, but it is not… (More)
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