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Interferon beta-1a

Known as: Interferon.beta 1a, beta 1a, Interferon, IFN-beta 
An interferon beta-1 subtype that has a methionine at position 1, a cysteine at position 17, and is glycosylated at position 80. It functions as an… 
National Institutes of Health

Related topics

Related topics

23 relations

Broader (3)

Antineoplastic AgentsAntiviral AgentsImmunologic Adjuvants

Narrower (3)

AvonexInterferon beta-1a 0.03 MG InjectionRebif
Avonex PenDrug AllergyIFNB1 geneIn Blood

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Signalling mechanisms for Toll‐like receptor‐activated neutrophil exocytosis: key roles for interleukin‐1‐receptor‐associated kinase‐4 and phosphatidylinositol 3‐kinase but not Toll/IL‐1 receptor…
Lipopolysaccharide (LPS) stimulates exocytosis in neutrophils. The signalling molecules involved in the regulation of this… 
2006
2006
Selective treatment of multiple sclerosis.
Natalizumab, a recombinant monoclonal antibody against α4 integrins, is the first selective immunomodulating drug for the… 
2005
2005
The Production of IL-1 Receptor Antagonist in IFN-β-Stimulated Human Monocytes Depends on the Activation of Phosphatidylinositol 3-Kinase but Not of STAT11
IFN-β induces the production of secreted IL-1R antagonist (sIL-1Ra) without triggering synthesis of the agonist IL-1β in human… 
2004
2004
Corticosteroids, ibuprofen, and acetaminophen for IFNβ-1a flu symptoms in MS
Objective: To compare the efficacy of acetaminophen, ibuprofen, and prednisone in the treatment of interferon β-1a (IFNβ-1a) flu… 
Highly Cited
2002
Highly Cited
2002
Both paracetamol and ibuprofen are equally effective in managing flu-like symptoms in relapsing-remitting multiple sclerosis patients during interferon beta-1a (AVONEX®) therapy
Interferon beta-1a is an established therapy for patients with relapsing-remitting multiple sclerosis (MS). Adverse effects in… 
2002
2002
Modulation of astrocyte inducible nitric oxide synthase and cytokine expression by interferon β is associated with induction and inhibition of interferon γ‐activated sequence binding activity
Although interferon (IFN)‐β is firmly established as a therapeutic agent for multiple sclerosis, information regarding its role… 
1998
1998
Evidence from Transgenic Mice That Interferon-β May Be Involved in the Onset of Diabetes Mellitus*
A number of cytokines have been shown to alter the function of pancreatic β-cells and thus might be involved in the development… 
1992
1992
Herpes simplex virus infection selectively stimulates accumulation of beta interferon reporter gene mRNA by a posttranscriptional mechanism
To study the mechanism of a novel herpes simplex virus (HSV) activity that stimulates expression of reporter genes containing… 
1984
1984
Induction and regulation of the 26-kDa protein in the absence of synthesis of beta-interferon mRNA in human cells.
The expression of the gene coding for the 26-kDa protein coinduced with human beta-interferon (HuIFN-beta) in human fibroblasts… 
1983
1983
Inhibition of human cytomegalovirus by trifluorothymidine
The antiviral activity of trifluorothymidine (TFT) singly and in combination with other antiviral agents against human… 
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