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Interferon beta-1a
Known as:
Interferon.beta 1a
, beta 1a, Interferon
, IFN-beta
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An interferon beta-1 subtype that has a methionine at position 1, a cysteine at position 17, and is glycosylated at position 80. It functions as an…
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National Institutes of Health
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Related topics
Related topics
23 relations
Broader (3)
Antineoplastic Agents
Antiviral Agents
Immunologic Adjuvants
Narrower (3)
Avonex
Interferon beta-1a 0.03 MG Injection
Rebif
Avonex Pen
Drug Allergy
IFNB1 gene
In Blood
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Human Cytomegalovirus IE86 Attenuates Virus- and Tumor Necrosis Factor Alpha-Induced NFκB-Dependent Gene Expression
R. Taylor
,
W. Bresnahan
Journal of Virology
2006
Corpus ID: 808663
ABSTRACT Human cytomegalovirus (HCMV) infection regulates a number of genes involved in the host antiviral response. We have…
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Highly Cited
2005
Highly Cited
2005
TLR4 and Toll-IL-1 Receptor Domain-Containing Adapter-Inducing IFN-β, but Not MyD88, Regulate Escherichia coli-Induced Dendritic Cell Maturation and Apoptosis In Vivo1
C. De Trez
,
B. Pajak
,
+5 authors
E. Muraille
Journal of Immunology
2005
Corpus ID: 5920737
Dendritic cells (DC) are short-lived, professional APCs that play a central role in the generation of adaptive immune responses…
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Highly Cited
2002
Highly Cited
2002
Autoimmune hepatitis and interferon beta-1a for multiple sclerosis
A. Duchini
American Journal of Gastroenterology
2002
Corpus ID: 19303562
1. Hanazaki K, Kajikawa S, Koide N, et al. Prognostic factors after hepatic resection for hepatocellular carcinoma with hepatitis…
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Highly Cited
1999
Highly Cited
1999
Inhibition of T cell apoptosis by IFN‐β rapidly reverses nuclear translocation of protein kinase C‐δ
D. Scheel-Toellner
,
D. Pilling
,
+4 authors
J. Lord
European Journal of Immunology
1999
Corpus ID: 13777223
Type I interferons rescue activated human T cells from cytokine deprivation‐induced apoptosis. Our data now show that IFN‐β also…
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Review
1998
Review
1998
IFN-tau: a novel subtype I IFN1. Structural characteristics, non-ubiquitous expression, structure-function relationships, a pregnancy hormonal embryonic signal and cross-species therapeutic…
J. Martal
,
N. Chêne
,
+5 authors
S. Y. Charpigny
Biochimie
1998
Corpus ID: 35555050
Highly Cited
1996
Highly Cited
1996
Circulating serum levels of IL-1ra in patients with relapsing remitting multiple sclerosis are normal during remission phases but significantly increased either during exacerbations or in response to…
F. Nicoletti
,
Francesco Patti
,
+4 authors
A. Reggio
Cytokine
1996
Corpus ID: 26224977
Interleukin (IL)-1 receptor antagonist (IL-1ra) is a naturally occurring inhibitor of IL-1 which binds to IL-1 receptors without…
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Highly Cited
1994
Highly Cited
1994
Viral induction of the human beta interferon promoter: modulation of transcription by NF-kappa B/rel proteins and interferon regulatory factors
Evgenia Garoufalis
,
I. Kwan
,
+6 authors
Terny Fox
Journal of Virology
1994
Corpus ID: 30785500
Multiple regulatory domains within the -100 region of the beta interferon (IFN-beta) promoter control the inducible response of…
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Highly Cited
1990
Highly Cited
1990
The human intracellular Mx‐homologous protein is specifically induced by type I interferons
P. von Wussow
,
D. Jakschies
,
H. Hochkeppel
,
C. Fibich
,
Lothar Penner
,
H. Deicher
European Journal of Immunology
1990
Corpus ID: 38838700
The murine Mx‐1 protein is one of the best biochemically and functionally characterized interferon (IFN)‐induced proteins that is…
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Highly Cited
1985
Highly Cited
1985
Induction of a 26-kDa-protein mRNA in human cells treated with an interleukin-1-related, leukocyte-derived factor.
J. Content
,
L. Wit
,
P. Poupart
,
G. Opdenakker
,
J. Damme
,
A. Billiau
European Journal of Biochemistry
1985
Corpus ID: 27223740
A human-leukocyte-derived antiviral protein (22-kDa factor), known to be an inducer of interferon-beta (IFN-beta) in…
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Highly Cited
1985
Highly Cited
1985
Interferon regulates c-myc gene expression in Daudi cells at the post-transcriptional level.
E. Knight
,
E. Antón
,
D. Fahey
,
B. Friedland
,
G. Jonak
Proceedings of the National Academy of Sciences…
1985
Corpus ID: 33250650
c-myc gene mRNA is reduced by greater than 75% in the human lymphoblastoid cell line Daudi when growth is inhibited by treatment…
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