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Insulin-Like Growth Factor Binding Protein 6

Known as: IGF-Binding Protein 6, IGF Binding Protein 6, IGFBP-6 
One of the six homologous soluble proteins that bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions at… 
National Institutes of Health

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IGFBP6 geneIn BloodProcess of secretionagonists

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IGFBP6 protein, human

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IGFBP6 wt Allele

Papers overview

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Review
2005
Review
2005
IGFBP-6 five years on; not so 'forgotten'?
Highly Cited
2001
Highly Cited
2001
No evidence of insulin-like growth factor-binding protein 3 proteolysis during a maximal exercise test in elite athletes.
The aim of the present study was to examine the GH/insulin-like growth factor (IGF) axis, post exercise, with emphasis on IGF… 
1999
1999
Hypoglycaemia associated with the production of insulin‐like growth factor II and insulin‐like growth factor binding protein 6 by a haemangiopericytoma
Non‐islet‐cell tumour‐induced hypoglycaemia (NICTH) is, in most cases, attributable to tumour production of insulin‐like growth… 
1997
1997
Growth factor regulation of insulin‐like growth factor binding protein‐6 expression in osteoblasts
Previously we have shown that transforming growth factor β (TGF β) 1, basic fibroblast growth factor (FGF), and platelet‐derived… 
1996
1996
Expression of the messenger ribonucleic acids for insulin-like growth factor-I and insulin-like growth factor binding proteins in porcine corpora lutea.
In the pig, the corpus luteum (CL) can develop and function autonomous of pituitary gonadotropins for approximately 12 days. We… 
Review
1996
Review
1996
The role of insulin-like growth factors and their binding proteins in tumor hypoglycemia.
Tumors of nonislet cell origin may overexpress insulin-like growth factor (IGF)-II, leading to hypoglycemia with suppressed serum… 
1996
1996
Insulin-like growth factor-binding protein-6 produced by human PC-3 prostate cancer cells: isolation, characterization and its biological action.
The PC-3 human prostatic carcinoma cell line has been extensively used as a model for studies on the regulation of prostate tumor… 
1994
1994
Regulation of immunoreactive insulin-like growth factor binding protein-6 in normal and transformed human fibroblasts.
Insulin-like growth factor-binding proteins (IGFBPs) have been shown to both potentiate and inhibit IGF bioactivity in vitro… 
Highly Cited
1993
Highly Cited
1993
Insulin-like growth factors and insulin-like growth factor binding proteins in cerebrospinal fluid and serum of patients with dementia of the Alzheimer type
SummaryAfter acid gelchromatography cerebrospinal fluid and serum levels of immunoreactive insulin-like growth factor 1 and 2… 
Highly Cited
1991
Highly Cited
1991
Isolation and molecular cloning of insulin-like growth factor-binding protein-6.
Insulin-like growth factors (IGFs) together with their binding proteins (BPs) are potential regulators of folliculogenesis in… 
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