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Ineffective erythropoiesis

Known as: Defective erythropoiesis 
National Institutes of Health

Related topics

Related topics

6 relations
5q-syndromeANEMIA, CONGENITAL DYSERYTHROPOIETIC, TYPE IVCongenital dyserythropoietic anemia, type IIHYPERBILIRUBINEMIA, SHUNT, PRIMARY
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Broader (1)

Dyserythropoiesis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Iron metabolism under conditions of ineffective erythropoiesis in β-thalassemia.
β-Thalassemia (BT) is an inherited genetic disorder that is characterized by ineffective erythropoiesis (IE), leading to anemia… Expand
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Review
2018
Review
2018
Ineffective Erythropoiesis: Anemia and Iron Overload.
Stress erythropoiesis (SE) is characterized by an imbalance in erythroid proliferation and differentiation under increased… Expand
Highly Cited
2014
Highly Cited
2014
Modified activin receptor IIB ligand trap mitigates ineffective erythropoiesis and disease complications in murine β-thalassemia.
In β-thalassemia, unequal production of α- and β-globin chains in erythroid precursors causes apoptosis and inhibition of late… Expand
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Review
2014
Review
2014
Sideroblastic anemia: diagnosis and management.
Sideroblastic anemias (SAs) may be acquired or congenital and share the features of disrupted utilization of iron in the… Expand
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Highly Cited
2013
Highly Cited
2013
Reducing TMPRSS6 ameliorates hemochromatosis and β-thalassemia in mice.
β-Thalassemia and HFE-related hemochromatosis are 2 of the most frequently inherited disorders worldwide. Both disorders are… Expand
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Highly Cited
2010
Highly Cited
2010
β-Thalassemia: HiJAKing Ineffective Erythropoiesis and Iron Overload
β-thalassemia encompasses a group of monogenic diseases that have in common defective synthesis of β-globin. The defects involved… Expand
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Review
2009
Review
2009
Pathophysiology of Transfusional Iron Overload: Contrasting Patterns in Thalassemia Major and Sickle Cell Disease
The pathophysiological consequences of transfusional iron overload largely reflect the pattern of excess iron distribution and… Expand
Highly Cited
2008
Highly Cited
2008
Decreased differentiation of erythroid cells exacerbates ineffective erythropoiesis in beta-thalassemia.
In beta-thalassemia, the mechanism driving ineffective erythropoiesis (IE) is insufficiently understood. We analyzed mice… Expand
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Highly Cited
2007
Highly Cited
2007
Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin.
Progressive iron overload is the most salient and ultimately fatal complication of beta-thalassemia. However, little is known… Expand
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1962
1962
Anæmia and Polycythæmia with Renal Disease
Red Cell Morphology in Renal Anemia In early studies by Ashe (1929) and Parsons and Ekola-Strolberg (I933) the anlemia was found… Expand
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