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Induction of Cell Senescence

Known as: Cell Senescence Induction, Positive Regulation of Cell Aging 
Any process that increases the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of… 
National Institutes of Health

Related topics

Related topics

11 relations
Cell AgingMAPKAPK5 geneMAPKAPK5 protein, humanMAPKAPK5 wt Allele

Broader (1)

biological control

Papers overview

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2018
2018
Targeting DTL induces cell cycle arrest and senescence and suppresses cell growth and colony formation through TPX2 inhibition in human hepatocellular carcinoma cells
Background Hepatocellular carcinoma (HCC) has an increasing incidence and high mortality. Surgical operation is not a… 
2017
2017
Resveratrol Attenuates Copper-Induced Senescence by Improving Cellular Proteostasis
Copper sulfate-induced premature senescence (CuSO4-SIPS) consistently mimetized molecular mechanisms of replicative senescence… 
2014
2014
Antiproliferative Effect of the Isoquinoline Alkaloid Papaverine in Hepatocarcinoma HepG-2 Cells — Inhibition of Telomerase and Induction of Senescence
Cancer cells are often immortal through up-regulation of the hTERT gene, which encodes the catalytic subunit of a special reverse… 
2012
2012
Induction of cell senescence by targeting to Cullin-RING Ligases (CRLs) for effective cancer therapy.
Cullin-RING ligases (CRLs) are the biggest family of multiunit ubiquitin E3 ligases, controlling many biological processes by… 
2012
2012
Persistent DNA damage caused by low levels of mitomycin C induces irreversible cell senescence
Mutations of oncogenes and tumor suppressor genes which activate mTOR through several downstream signaling pathways are common to… 
2010
2010
Another "Janus paradox" of p53: induction of cell senescence versus quiescence
No other protein shows such multiplicity and diversity of functions as the tumor suppressor p53 [1, 2]. Initially, the role of… 
2010
2010
New Biomarkers Probing Depth of Cell Senescence Assessed by Laser Scanning Cytometry
The imaging analytical capabilities of laser scanning cytometer (LSC) have been used to assess morphological features considered… 
2009
2009
Chronic inflammation potentiates kidney aging.
2009
2009
Involvement of hydrogen peroxide in histamine-induced modulation of WM35 human malignant melanoma cell proliferation.
2007
2007
hAda3 regulates p14ARF-induced p53 acetylation and senescence
Acetylation is thought to be a key event for p53 activation. We demonstrate that p14ARF-induced senescence of human mammary… 
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