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Incretins
Known as:
incretin hormone
, Hormone, Glucose-Dependent Insulin-Releasing
, Glucose-Dependent Insulin-Releasing Hormone
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Peptides which stimulate INSULIN release from the PANCREATIC BETA CELLS following oral nutrient ingestion, or postprandially.
National Institutes of Health
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Related topics
Related topics
21 relations
Narrower (8)
Gastric Inhibitory Polypeptide
Glucagon-Like Peptide 1
Linagliptin
alogliptin
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Broader (2)
Gastrointestinal Hormones
Peptides
Glucagon-Like Peptides
In Blood
Incretin Effect
Process of secretion
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
Incretin-based therapies for type 2 diabetes mellitus
J. Lovshin
,
D. Drucker
Nature Reviews Endocrinology
2009
Corpus ID: 3101759
Incretin-based drugs, such as glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase 4 inhibitors, are now routinely…
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Review
2008
Review
2008
The Role of Incretins in Glucose Homeostasis and Diabetes Treatment
Wook Kim
,
Josephine M. Egan
Pharmacological Reviews
2008
Corpus ID: 262252191
Incretins are gut hormones that are secreted from enteroendocrine cells into the blood within minutes after eating. One of their…
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Review
2007
Review
2007
Biology of incretins: GLP-1 and GIP.
L. Baggio
,
D. Drucker
Gastroenterology
2007
Corpus ID: 24778231
This review focuses on the mechanisms regulating the synthesis, secretion, biological actions, and therapeutic relevance of the…
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Review
2007
Review
2007
Efficacy and safety of incretin therapy in type 2 diabetes: systematic review and meta-analysis.
Renee E. Amori
,
J. Lau
,
A. Pittas
Journal of the American Medical Association (JAMA…
2007
Corpus ID: 10243493
CONTEXT Pharmacotherapies that augment the incretin pathway have recently become available, but their role in the management of…
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Highly Cited
2006
Highly Cited
2006
Reduced incretin effect in Type 2 (non-insulin-dependent) diabetes
M. Nauck
,
F. Stöckmann
,
R. Ebert
,
W. Creutzfeldt
Diabetologia
2006
Corpus ID: 6146335
SummaryIntegrated incremental immunoreactive insulin and connecting peptide responses to an oral glucose load of 50 g and an…
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Review
2006
Review
2006
The biology of incretin hormones.
D. Drucker
Cell Metabolism
2006
Corpus ID: 19401832
Review
2006
Review
2006
The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
D. Drucker
,
M. Nauck
The Lancet
2006
Corpus ID: 25748028
Highly Cited
2005
Highly Cited
2005
Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120
A. Hirasawa
,
K. Tsumaya
,
+6 authors
G. Tsujimoto
Nature Network Boston
2005
Corpus ID: 36845443
Diabetes, a disease in which the body does not produce or use insulin properly, is a serious global health problem. Gut…
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Highly Cited
1993
Highly Cited
1993
Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus.
M. Nauck
,
M. Heimesaat
,
C. Ørskov
,
J. Holst
,
R. Ebert
,
W. Creutzfeldt
Journal of Clinical Investigation
1993
Corpus ID: 13978252
In type-2 diabetes, the overall incretin effect is reduced. The present investigation was designed to compare insulinotropic…
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Highly Cited
1986
Highly Cited
1986
Incretin effects of increasing glucose loads in man calculated from venous insulin and C-peptide responses.
M. Nauck
,
E. Homberger
,
+4 authors
W. Creutzfeldt
Journal of Clinical Endocrinology and Metabolism
1986
Corpus ID: 24776363
Integrated insulin secretion rates calculated from peripheral venous C-peptide measurements by two-compartment kinetic analysis…
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