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Inactivation, Metabolic

Known as: Metabolic Inactivation 
Reduction of pharmacologic activity or toxicity of a drug or other foreign substance by a living system, usually by enzymatic action. It includes… 
National Institutes of Health

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Metabolic Detoxication, Drug
aspects of radiation effectsphysiological aspects

Papers overview

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Review
2013
Review
2013
Drug Delivery using genetically modified Mesenchymal Stem Cells: A promising targeted-delivery method
Plan: The review covers the unique role of Mesenchymal stem cells to improve, the poor solubility, premature metabolic… 
2011
2011
Structure-based design of dipeptide derivatives for the human neutral endopeptidase.
2006
2006
Effects of paclitaxel, docetaxel and their combinations on subcutaneous lymphomas in inbred Sprague-Dawley/Cub rats.
2004
2004
β-Methyl-digoxin
SummaryGlycosides were injected into a ligated loop of the small intestine of guinea-pigs under urethane anaesthesia. From the… 
2001
2001
Verapamil metabolism in distinct regions of the heart and in cultures of cardiomyocytes of adult rats.
A substantial number of drugs act either directly or indirectly on the heart, but surprisingly, little is known about drug… 
Review
1982
Review
1982
Does sulfate conjugation contribute to the metabolic inactivation of catecholamines in humans?
1979
1979
Analysis and differentiation of mechanism of tolerance to methadone in methadone-fed rats.
1975
1975
Microsomal enzyme induction by methadone and its implications on tolerance to methadone lethality
MANY investigators have sought to explain narcotic tolerance as a result of increased metabolic inactivation of the drug. No… 
Review
1974
Review
1974
[Carcinogenic environmental substances. Test methods and metabolic inactivation].
1967
1967
Calcium transport in isolated guinea-pig atria during metabolic inhibition.
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