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Inactivation, Metabolic

Known as: Metabolic Inactivation 
Reduction of pharmacologic activity or toxicity of a drug or other foreign substance by a living system, usually by enzymatic action. It includes… 
National Institutes of Health

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Metabolic Detoxication, Drug
aspects of radiation effectsphysiological aspects

Papers overview

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Highly Cited
2015
Highly Cited
2015
Investigation of the interactions of silibinin with 2-hydroxypropyl-β-cyclodextrin through biophysical techniques and computational methods.
Cyclodextrins (CDs) are a well-known class of supermolecules that have been widely used to protect drugs against conjugation and… 
2014
2014
Pharmacokinetic and pharmacodynamics studies of nicotine after oral administration in mice: effects of methoxsalen, a CYP2A5/6 inhibitor.
INTRODUCTION The use of novel oral nicotine delivery devices and compositions for human consumption and for animal research… 
2011
2011
Structure-based design of dipeptide derivatives for the human neutral endopeptidase.
2007
2007
Oxidative metabolism of lipoamino acids and vanilloids by lipoxygenases and cyclooxygenases.
2006
2006
Effects of paclitaxel, docetaxel and their combinations on subcutaneous lymphomas in inbred Sprague-Dawley/Cub rats.
1989
1989
Metabolic inactivation of leukotrienes.
Review
1982
Review
1982
Does sulfate conjugation contribute to the metabolic inactivation of catecholamines in humans?
1979
1979
Analysis and differentiation of mechanism of tolerance to methadone in methadone-fed rats.
1975
1975
Microsomal enzyme induction by methadone and its implications on tolerance to methadone lethality
MANY investigators have sought to explain narcotic tolerance as a result of increased metabolic inactivation of the drug. No… 
1967
1967
Calcium transport in isolated guinea-pig atria during metabolic inhibition.
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