Immunoglobulin A

Known as: IgA, Immunoglobulin A [Chemical/Ingredient], immunoglobulin a (IgA) 
Represents 15-20% of the human serum immunoglobulins, mostly as the 4-chain polymer in humans or dimer in other mammals. Secretory IgA… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
BACKGROUND In the RV144 trial, the estimated efficacy of a vaccine regimen against human immunodeficiency virus type 1 (HIV-1… (More)
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Review
2008
Review
2008
The gut mucosa is exposed to a large community of commensal bacteria that are required for the processing of nutrients and the… (More)
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Highly Cited
2008
Highly Cited
2008
Immunoglobulin A (IgA) is generated in the gut by both T cell-dependent and T cell-independent processes. The sites and the… (More)
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Highly Cited
2007
Highly Cited
2007
Bacteria colonize the intestine shortly after birth and thereafter exert several beneficial functions, including induction of… (More)
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Highly Cited
2007
Highly Cited
2007
Epithelial cells (ECs) transport class-switched immunoglobulin G (IgG) and IgA antibodies across mucous membranes. Whether ECs… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Celiac disease (CD) is an immune-mediated enteropathic condition triggered in genetically susceptible individuals by… (More)
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Review
2002
Review
2002
IgA, IgG and IgM are transported across epithelial cells in a receptor-mediated process known as transcytosis. In addition to… (More)
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Highly Cited
2000
Highly Cited
2000
The immunoglobulin A (IgA) is produced to defend mucosal surfaces from environmental organisms, but host defenses against the… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND The gastrointestinal microflora is an important constituent of the gut mucosal defense barrier. We have previously… (More)
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Highly Cited
1994
Highly Cited
1994
An engagement of CD40 with CD40 ligand (CD40L) expressed on activated T cells is known to provide an essential costimulatory… (More)
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