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IgM B cell receptor complex

Known as: IgM B cell receptor complex location, surface IgM 
An IgM immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Anergic Responses Characterize a Large Fraction of Human Autoreactive Naive B Cells Expressing Low Levels of Surface IgM
B cell anergy represents an important mechanism of peripheral immunological tolerance for mature autoreactive B cells that escape… Expand
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Highly Cited
2004
Highly Cited
2004
Signaling through CD70 Regulates B Cell Activation and IgG Production
CD70, the cellular ligand of the TNF receptor family member CD27, is expressed transiently on activated T and B cells and… Expand
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Highly Cited
1998
Highly Cited
1998
Long-lived B cells are distinguished by elevated expression of A1.
Only 5% of the 15 million B cells formed daily reach the long-lived peripheral B cell pool, presumably reflecting both negative… Expand
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Highly Cited
1998
Highly Cited
1998
CD40 engagement triggers switching to IgA1 and IgA2 in human B cells through induction of endogenous TGF-beta: evidence for TGF-beta but not IL-10-dependent direct S mu-->S alpha and sequential S mu…
IgA are major effectors of antimicrobial defense in the respiratory and digestive tracts. We have analyzed the requirements for… Expand
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Highly Cited
1997
Highly Cited
1997
Apoptosis during B lymphopoiesis in mouse bone marrow.
To evaluate the magnitude of cell death and the critical stages at which it occurs during B lymphopoiesis in mouse bone marrow… Expand
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Highly Cited
1996
Highly Cited
1996
Maintenance of nuclear factor-kappa B/Rel and c-myc expression during CD40 ligand rescue of WEHI 231 early B cells from receptor-mediated apoptosis through modulation of I kappa B proteins.
Engagement of surface IgM (sIgM) on WEHI 231 murine B lymphoma cells leads to abortive activation and apoptosis, suggesting that… Expand
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Highly Cited
1995
Highly Cited
1995
Selective Activation of c-Jun Kinase Mitogen-activated Protein Kinase by CD40 on Human B Cells (*)
The B cell surface antigen receptor, surface IgM (sIgM), is involved in B cell activation and proliferation. CD40 is involved in… Expand
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Highly Cited
1993
Highly Cited
1993
Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells.
Recently the cDNA encoding interleukin 13 (IL-13), a T-cell-derived cytokine, was cloned and expressed. The present study… Expand
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Highly Cited
1993
Highly Cited
1993
CD22 associates with the human surface IgM-B-cell antigen receptor complex.
The B-cell surface molecule CD22, when cross-linked, modulates signaling through the surface IgM (sIgM)-B-cell receptor (BCR… Expand
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Highly Cited
1976
Highly Cited
1976
Ontogeny of B cells in the chicken. I. Sequential development of clonal diversity in the bursa
The initial development and distribution of lymphocytes expressing surface IgM (sIgM) and of specific antigen-binding cells (ABC… Expand
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