Idiopathic Nephrotic Syndrome

Known as: NEPHROTIC SYNDROME, TYPE 2, NPHS2, Nephrotic Syndrome, Idiopathic 
Nephrotic syndrome for which no cause has been identified.(NICHD)
National Institutes of Health

Related topics

Related topics

12 relations
Autosomal recessive inheritanceEdemaFocal glomerulosclerosisHyperlipidemia
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Broader (1)

Nephrosis, congenital

Papers overview

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Highly Cited
2015
Highly Cited
2015
A single-gene cause in 29.5% of cases of steroid-resistant nephrotic syndrome.
Steroid-resistant nephrotic syndrome (SRNS) is the second most frequent cause of ESRD in the first two decades of life. Effective… (More)
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Highly Cited
2014
Highly Cited
2014
Rituximab in steroid-dependent or frequently relapsing idiopathic nephrotic syndrome.
The outcome of steroid-dependent or frequently relapsing nephrotic syndrome of minimal change disease (MCD), mesangial… (More)
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Highly Cited
2010
Highly Cited
2010
Immunosuppression and renal outcome in congenital and pediatric steroid-resistant nephrotic syndrome.
BACKGROUND AND OBJECTIVES Mutations in podocyte genes are associated with steroid-resistant nephrotic syndrome (SRNS), mostly… (More)
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Highly Cited
2008
Highly Cited
2008
Rituximab treatment for severe steroid- or cyclosporine-dependent nephrotic syndrome: a multicentric series of 22 cases
Several case reports suggest that rituximab (RTX) could be effective in steroid-dependent nephrotic syndrome, but RTX efficacy… (More)
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Highly Cited
2004
Highly Cited
2004
Patients with mutations in NPHS2 (podocin) do not respond to standard steroid treatment of nephrotic syndrome.
Nephrotic syndrome (NS) represents the association of proteinuria, hypoalbuminemia, edema, and hyperlipidemia. Steroid-resistant… (More)
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Highly Cited
2004
Highly Cited
2004
NPHS2 mutation analysis shows genetic heterogeneity of steroid-resistant nephrotic syndrome and low post-transplant recurrence.
BACKGROUND Mutations of NPHS2 are causative in familial autosomal-recessive (AR) and sporadic steroid-resistant nephrotic… (More)
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Review
2003
Review
2003
Nephrotic syndrome in childhood
Childhood nephrotic syndromes are most commonly caused by one of two idiopathic diseases: minimal-change nephrotic syndrome (MCNS… (More)
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Highly Cited
2001
Highly Cited
2001
Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin.
NPHS2 was recently identified as a gene whose mutations cause autosomal recessive steroid-resistant nephrotic syndrome. Its… (More)
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Highly Cited
2000
Highly Cited
2000
NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome
Familial idiopathic nephrotic syndromes represent a heterogeneous group of kidney disorders, and include autosomal recessive… (More)
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Highly Cited
1993
Highly Cited
1993
A randomized trial of cyclosporine in steroid-resistant idiopathic nephrotic syndrome
To compare the efficacy (induction of remission) and safety of cyclosporine (CsA) with those of supportive therapy in patients… (More)
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