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Idiopathic Central Precocious Puberty

Central precocious puberty for which no underlying cause can be identified.
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Mutations in the maternally imprinted gene MKRN3 are common in familial central precocious puberty.
CONTEXT AND OBJECTIVE Idiopathic central precocious puberty (iCPP) is defined as early activation of the hypothalamic-pituitary… 
2014
2014
Urinary Bisphenol A Levels in Girls with Idiopathic Central Precocious Puberty
Objective: Bisphenol A (BPA) is an industrial chemical, particularly used to harden plastics. BPA is thought to have negative… 
2014
2014
Mutational analysis of KISS1 and KISS1R in idiopathic central precocious puberty
Abstract Aim: The genetic background of idiopathic central precocious puberty (ICPP) is not well understood. The genetic… 
Review
2012
Review
2012
A potential mechanism for the sexual dimorphism in the onset of puberty and incidence of idiopathic central precocious puberty in children: sex-specific kisspeptin as an integrator of puberty signals
The major determinants of the variability in pubertal maturation are reported to be genetic and inherited. Nonetheless… 
2011
2011
LIN28B, LIN28A, KISS1, and KISS1R in idiopathic central precocious puberty
BackgroundPubertal timing is a strongly heritable trait, but no single puberty gene has been identified. Thus, the genetic… 
Highly Cited
2011
Highly Cited
2011
Adult height, body mass index and time of menarche of girls with idiopathic central precocious puberty after gonadotropin-releasing hormone analogue treatment
Background. Long-term outcome data of central precocious puberty (CPP) girls treated with gonadotropin-releasing hormone analogue… 
2011
2011
The effect of gonadotropin-releasing hormone analog treatment (leuprolide) on body fat distribution in idiopathic central precocious puberty.
Gonadotropin-releasing hormone analog (GnRHa) therapy is used in idiopathic central precocious puberty (ICPP) worldwide. It has… 
Highly Cited
2002
Highly Cited
2002
Factors predicting adult height in girls with idiopathic central precocious puberty: implications for treatment *
objectives To optimize the indications for treating girls with idiopathic central precocious puberty with GnRH analogues, since… 
Highly Cited
1998
Highly Cited
1998
Central precocious puberty in girls: internal genitalia before, during, and after treatment with long-acting gonadotropin-releasing hormone analogues.
1995
1995
Long-term GnRH-agonist treatment does not postpone central development of the GnRH pule generator in girls with idiopathic precocious puberty.
Gonadotropin and estradiol secretion were studied in two groups of female patients with idiopathic central precocious puberty, at… 
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