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Icotinib Hydrochloride

An orally available quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), with potential antineoplastic activity. Icotinib… 
National Institutes of Health

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BPI-2009H
NCIt Antineoplastic Agent TerminologyReceptor Tyrosine Kinase Inhibition

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Comparison of the efficacy of icotinib in patients with non-small-cell lung cancer according to the type of epidermal growth factor receptor mutation.
Icotinib hydrochloride is a novel epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) with preclinical and… 
2015
2015
Personalized biomarkers to monitor disease progression in advanced non-small-cell lung cancer patients treated with icotinib.
2014
2014
Dramatic response to high-dose icotinib in a lung adenocarcinoma patient after erlotinib failure.
2013
2013
Efficacy and safety evaluation of icotinib in patients with advanced non-small cell lung cancer.
OBJECTIVE To evaluate the efficacy and safety of icotinib hydrochloride in patients with advanced non-small cell lung cancer… 
2013
2013
盐酸埃克替尼一线治疗晚期肺腺癌的临床疗效观察
背景与目的 分子靶向治疗药物盐酸埃克替尼治疗复治晚期非小细胞肺癌具有较好的疗效和安全性。本文观察盐酸埃克替尼一线治疗晚期肺腺癌的近期疗效和毒副反应。 方法 对2011年8月-2012年11月间收治的56例初治晚期肺腺癌患者，口服盐酸埃克替尼125 mg… 
2013
2013
盐酸埃克替尼治疗晚期复发非小细胞肺癌的临床疗效
背景与目的 盐酸埃克替尼是第三个在临床上应用于晚期非小细胞肺癌（non-small cell lung cancer, NSCLC）治疗的单靶点表皮生长因子受体酪氨酸激酶抑制剂（epidermal growth factor receptor… 
2012
2012
[Clinical observation of icotinib hydrochloride for patients with advanced non-small cell lung cancer].
OBJECTIVE To explore the efficacy and side effects of icotinib hydrochloride in the treatment of patients with advanced non-small… 
2011
2011
Tumor gene mutations and messenger RNA expression: correlation with clinical response to icotinib hydrochloride in non-small cell lung cancer.
BACKGROUND Molecular targeted drugs is now widely used in non-small cell lung cancer (NSCLC) clinical treatment. Icotinib… 
2009
2009
Quantitative determination of icotinib in human plasma and urine using liquid chromatography coupled to tandem mass spectrometry.
Review
2009
Review
2009
Pharmacology and clinical evaluation of icotinib hydrochloride
Icotinib hydrochloride is a novel oral epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI).It is indicated for… 
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