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ITPR1 wt Allele

Known as: ITPR1, IP3R, Inositol 1,4,5-Triphosphate Receptor, Type 1 Gene 
Human ITPR1 wild-type allele is located within 3p26-p25 and is approximately 354 kb in length. This allele, which encodes inositol 1,4,5… Expand
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
The present study used perforated-patch electrophysiology and calcium imaging in GnRH transgenic mouse lines to determine the… Expand
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Highly Cited
2007
Highly Cited
2007
We observed a severe autosomal recessive movement disorder in mice used within our laboratory. We pursued a series of experiments… Expand
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Review
2001
Review
2001
Activation of most excitatory synapses of central neurons produces calcium release signals from intracellular stores… Expand
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Highly Cited
2000
Highly Cited
2000
Rho-type GTPases control many cytoskeletal rearrangements, but their regulation remains poorly understood. Here, we show that in… Expand
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Highly Cited
2000
Highly Cited
2000
The p21-activated kinases (PAKs) are effectors for the Rho-family GTPase Cdc42p. Here we define the in vivo function of the… Expand
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Highly Cited
1997
Highly Cited
1997
Stimulation of B‐cell antigen receptor (BCR) induces a rapid increase in cytoplasmic free calcium due to its release from… Expand
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Highly Cited
1997
Highly Cited
1997
The type 1 inositol 1,4,5-trisphosphate receptor (IP3R1) calcium release channel is present on the endoplasmic reticulum of most… Expand
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Highly Cited
1996
Highly Cited
1996
THE inositol 1,4,5-trisphosphate (InsP3) receptor acts as an InsP3-gated Ca2+ release channel in a variety of cell types1,2. Type… Expand
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Highly Cited
1996
Highly Cited
1996
STE20 encodes a protein kinase related to mammalian p65Pak which functions in several signal transduction pathways in yeast… Expand
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Highly Cited
1995
Highly Cited
1995
The yeast Ste20 protein kinase is involved in pheromone response. Mammalian homologs of Ste20 exist, but their function remains… Expand
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