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ITGB4 protein, human

Known as: GP150, integrin, beta 4 protein, human, GP150 protein, human 
Integrin beta-4 (1822 aa, ~202 kDa) is encoded by the human ITGB4 gene. This protein is involved in epithelial cell adhesion.
National Institutes of Health

Related topics

Related topics

11 relations
Cell AdhesionCell-Cell Adhesion ProcessClusters of differentiationFocal adhesion pathway

Broader (1)

Integrin beta4

Papers overview

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2019
2019
Dose dependency PM2.5 aggravated airway inflammation in asthmatic mice via down-regulating expression of ITGB4.
OBJECTIVE We aimed to investigate whether PM2.5 has the potential to exacerbate neutrophil airway inflammation and to analyze the… 
2015
2015
Suppression of ITGB4 Gene Expression in PC-3 Cells with Short Interfering RNA Induces Changes in the Expression of β-Integrins Associated with RGD-Receptors
We studied the effect of transfection of PC-3 prostate cancer cells with a plasmid encoding shRNA complimentary to a fragment of… 
Highly Cited
2005
Highly Cited
2005
Copy number aberrations in mouse breast tumors reveal loci and genes important in tumorigenic receptor tyrosine kinase signaling.
Receptor tyrosine kinase (RTK) signaling plays a key role in the development of breast cancer. Defining the genes and pathways in… 
2004
2004
Murine Gammaherpesvirus (MHV) M7 Gene Encoding Glycoprotein 150 (gp150): Difference in the Sequence between 72 and 68 Strains
Murine gammaherpesvirus 72 (MHV-72) was isolated from the same species of free-living small rodent as MHV-68 which currently… 
2002
2002
Increased expression of integrin β‐4 in papillary thyroid carcinoma with gross lymph node metastasis
Although the prognosis is generally good for patients with papillary thyroid carcinoma, gross nodal metastasis of carcinoma has a… 
1998
1998
Single Glycosyltransferase, Core 2 β1→6-N-acetylglucosaminyltransferase, Regulates Cell Surface Sialyl-Lex Expression Level in Human Pre-B Lymphocytic Leukemia Cell Line KM3 Treated with Phorbolester…
Sialyl-Lex (sLex) antigen expression recognized by KM93 monoclonal antibody was significantly down-regulated during… 
Highly Cited
1991
Highly Cited
1991
Differentially regulated cell surface expression of leukocyte adhesion receptors on neutrophils.
To elucidate the molecular mechanisms accounting for hemodialysis-induced neutropenia, the regulation of plasma membrane… 
Highly Cited
1989
Highly Cited
1989
Adhesion molecules on the plasma membrane of epidermal cells. I. Human resting Langerhans cells express two members of the adherence-promoting CD11/CD18 family, namely, H-Mac-1 (CD11b/CD18) and gp…
The CD11/CD18 family of leukocyte adhesion-promoting proteins is comprised of three members, each composed of a shared beta… 
1989
1989
Bone marrow and tissue expression of gpIIb/IIIa, LFA‐1, Mac‐1 and gp150,95 glycoproteins
Monoclonal antibodies (MAbs) against platelet glycoprotein gpIIb/IIIa and the leucocyte adhesion molecules LFA‐1, Mac‐1, and gp… 
Review
1988
Review
1988
Molecular mechanisms of cell-cell interaction in Dictyostelium discoideum.
During development of the cellular slime mold Dictyostelium discoideum, cells migrate in response to cAMP to form aggregates… 
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