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ISC-4 compound
Known as:
phenylbutyl isoselenocyanate
National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
Organoselenium Compounds
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Abstract 2712: ISC-4, a novel inhibitor of hedgehog-Gli signaling, inhibits growth of CSC and CTC of melanoma patients
Arun K. Sharma
,
J. Jani
,
+11 authors
Jay Sharma
2014
Corpus ID: 54112102
Melanoma is one of the most aggressive cancers, and its incidence and mortality rate are on rise since no treatment options are…
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2013
2013
The Akt Inhibitor ISC-4 Synergizes with Cetuximab in 5-FU-Resistant Colon Cancer
J. Allen
,
J. Gallant
,
+4 authors
W. El-Deiry
PLoS ONE
2013
Corpus ID: 7622467
Phenylbutyl isoselenocyanate (ISC-4) is an Akt inhibitor with demonstrated preclinical efficacy against melanoma and colon cancer…
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2013
2013
Correction: The Akt Inhibitor ISC-4 Synergizes with Cetuximab in 5-FU-Resistant Colon Cancer
J. Allen
,
J. Gallant
,
+4 authors
W. El-Deiry
PLoS ONE
2013
Corpus ID: 72906248
There is an error in the title of Supplemental Table S2. The table describes the combinatorial effects of ISC-4, not TIC10. The…
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2011
2011
The Akt Inhibitor ISC-4 Activates Prostate Apoptosis Response Protein-4 and Reduces Colon Tumor Growth in a Nude Mouse Model
Arun K. Sharma
,
C. L. Kline
,
A. Berg
,
S. Amin
,
R. Irby
Clinical Cancer Research
2011
Corpus ID: 31299463
Purpose: Prostate apoptosis response protein-4 (Par-4) sensitizes cells to chemotherapy; however, Akt1 inactivates Par-4…
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2011
2011
Cancer Therapy : Preclinical The Akt Inhibitor ISC-4 Activates Prostate Apoptosis Response Protein-4 and Reduces Colon Tumor Growth in a Nude Mouse Model
Arun K. Sharma
,
C. L. Kline
,
A. Berg
,
S. Amin
,
R. Irby
2011
Corpus ID: 26243696
Purpose: Prostate apoptosis response protein-4 (Par-4) sensitizes cells to chemotherapy; however, Akt1 inactivates Par-4…
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2007
2007
The synthesis of 1-thia-6-oxa-6alambda(4)-seleno-3-azapentalene and a 3H-1,2,4-dithiazole.
M. Koketsu
,
Toshihiro Otsuka
,
D. Swenson
,
H. Ishihara
Organic and biomolecular chemistry
2007
Corpus ID: 9361296
The reaction of thiocarbamoyl isoselenocyanate with a carbanion gave 1-thia-6-oxa-6alambda(4)-seleno-3-azapentalene, which has a…
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