IRF3 gene

Known as: INTERFERON REGULATORY FACTOR 3, IRF3, Interferon Regulatory Factor 3 Gene 
This gene plays a role in the transcriptional activation of target genes.
National Institutes of Health

Papers overview

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2015
2015
Herpes simplex encephalitis (HSE) in children has previously been linked to defects in type I interferon (IFN) production… (More)
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2010
2010
In mammals, IFN regulatory factor (IRF) 3 is a critical player in modulating transcription of type I IFN and IFN-stimulated genes… (More)
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2008
2008
In order to identify a novel candidate gene in systemic lupus erythematosus (SLE), we analysed a panel of six genes encoding… (More)
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Highly Cited
2008
Highly Cited
2008
Interferon regulatory factors (IRF) 3 and 7 in mammals are known to be crucial in regulating the type I interferon (IFN) response… (More)
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Highly Cited
2008
Highly Cited
2008
V accessory proteins from Paramyxoviruses are important in viral evasion of the innate immune response. Here, using a cell… (More)
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Highly Cited
2007
Highly Cited
2007
Interferon regulatory factor 3 (IRF3) is a key transcription factor involved in the induction of interferon (IFN) in response to… (More)
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Highly Cited
2005
Highly Cited
2005
Antiviral immunity against a pathogen is mounted upon recognition by the host of virally associated structures. One of these… (More)
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Highly Cited
2005
Highly Cited
2005
Virus-responsive signaling pathways that induce alpha/beta interferon production and engage intracellular immune defenses… (More)
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Highly Cited
2002
Highly Cited
2002
Ubiquitously expressed interferon regulatory factor 3 (IRF-3) is directly activated after virus infection and functions as a key… (More)
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Highly Cited
1998
Highly Cited
1998
Interferon establishes an antiviral state in numerous cell types through the induction of a set of immediate-early response genes… (More)
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