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IRAK3 wt Allele

Known as: IRAK-M, ASRT5, Interleukin-1 Receptor-Associated Kinase 3 wt Allele 
Human IRAK3 wild-type allele is located in the vicinity of 12q14.3 and is approximately 60 kb in length. This allele, which encodes interleukin-1… 
National Institutes of Health

Related topics

Related topics

4 relations
12q14.1Protein phosphorylationSignal Transduction

Broader (1)

IRAK3 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Neutrophils Deficient in Innate Suppressor IRAK-M Enhances Anti-tumor Immune Responses.
Review
2018
Review
2018
New Insights on Neuronal Nicotinic Acetylcholine Receptors as Targets for Pain and Inflammation: A Focus on α7 nAChRs
Background Nicotine and nicotinic acetylcholine receptors (nAChRs) have been explored for the past three decades as targets for… 
2017
2017
THU0224 Association of IRAK-M with neuropsychiatric symptoms in systemic lupus erythematosus patients
Background Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune disease, where a breakdown in immune tolerance… 
Review
2016
Review
2016
Immunoregulatory Effects Triggered by Lactic Acid Bacteria Exopolysaccharides: New Insights into Molecular Interactions with Host Cells
Researchers have demonstrated that lactic acid bacteria (LAB) with immunomodulatory capabilities (immunobiotics) exert their… 
2015
2015
Tolerance and Cross-Tolerance following Toll-Like Receptor (TLR)-4 and -9 Activation Are Mediated by IRAK-M and Modulated by IL-7 in Murine Splenocytes
Objective Immune suppression during critical illness predisposes to serious infections. We sought to determine the mechanisms… 
2013
2013
Wear particles promote endotoxin tolerance in macrophages by inducing interleukin-1 receptor-associated kinase-M expression.
Toll-like receptors (TLRs) recognizing pathogen-associated molecular patterns (PAMP) play a role in local immunity and… 
Highly Cited
2012
Highly Cited
2012
IL-13 dampens human airway epithelial innate immunity through induction of IL-1 receptor-associated kinase M.
2011
2011
Carbonylation caused by cigarette smoke extract is associated with defective macrophage immunity.
Oxidants in cigarette smoke inhibit pathogen recognition receptor function and phagocytosis, but the molecular basis of this… 
2007
2007
Biliary innate immunity and cholangiopathy
The intrahepatic biliary tree is a conduit of bile which contains pathogen‐associated molecular patterns (PAMPs) such as… 
2007
2007
Association of interleukin-1 receptor-associated kinase M (IRAK-M) and inflammatory bowel diseases
Objective. Inflammatory bowel diseases (IBD) have a complex genetic background. The interleukin receptor associated kinase-M… 
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