FAQ

IPP gene

Known as: kelch-like family member 27, INTRACISTERNAL A PARTICLE-PROMOTED POLYPEPTIDE, KLHL27 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1969-2017
0204019692017

Papers overview

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Highly Cited
2009
Highly Cited
2009
Peripheral blood monocytes are responsible for gammadelta T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP.
Nitrogen-containing bisphosphonates indirectly activate Vgamma9Vdelta2 T cells through inhibition of farnesyl pyrophosphate… (More)
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Highly Cited
2007
Highly Cited
2007
Evidence of artemisinin production from IPP stemming from both the mevalonate and the nonmevalonate pathways
The potent antimalarial sesquiterpene lactone, artemisinin, is produced in low quantities by the plant Artemisia annua L. The… (More)
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2007
2007
Crystal structure of 1-deoxy-D-xylulose 5-phosphate synthase, a crucial enzyme for isoprenoids biosynthesis.
Isopentenyl pyrophosphate (IPP) is a common precursor for the synthesis of all isoprenoids, which have important functions in… (More)
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2006
2006
Alkylamines cause Vgamma9Vdelta2 T-cell activation and proliferation by inhibiting the mevalonate pathway.
Three general classes of small, nonpeptide "antigens" activate Vgamma9Vdelta2 T cells: pyrophosphomonoesters, such as isopentenyl… (More)
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Highly Cited
2005
Highly Cited
2005
Reciprocal activating interaction between dendritic cells and pamidronate-stimulated gammadelta T cells: role of CD86 and inflammatory cytokines.
We investigated the interactions between human monocyte-derived dendritic cells (DCs) and Ag-activated circulating TCR-gammadelta… (More)
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2004
2004
Integrated Product Policy and Environmental Product Innovations: An Empirical Analysis
The European Commission has recently stepped up its promotion of the ‘Integrated Product Policy’. The objective of the IPP is to… (More)
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Highly Cited
2002
Highly Cited
2002
Reliability modeling of distributed generation in conventional distribution systems planning and analysis
The primary objective of any electric utility company in the new competitive environment is to increase the market value of the… (More)
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2001
2001
An unusual isopentenyl diphosphate isomerase found in the mevalonate pathway gene cluster from Streptomyces sp. strain CL190.
A gene cluster encoding five enzymes of the mevalonate pathway had been cloned from Streptomyces sp. strain CL190. This gene… (More)
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2000
2000
Activation of C-C beta-chemokines in human peripheral blood gammadelta T cells by isopentenyl pyrophosphate and regulation by cytokines.
Human gammadelta T lymphocytes respond to viral, bacterial, protozoal, and tumoral antigens, but their precise function remains… (More)
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Highly Cited
1999
Highly Cited
1999
Farnesyl pyrophosphate synthase is the molecular target of nitrogen-containing bisphosphonates.
Bisphosphonates (Bps), inhibitors of osteoclastic bone resorption, are used in the treatment of skeletal disorders. Recent… (More)
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