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INVS gene

Known as: NEPHROCYSTIN 2, INVERSION OF EMBRYONIC TURNING, INVERSIN 
National Institutes of Health

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NEPHRONOPHTHISIS 2

Papers overview

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Highly Cited
2008
Highly Cited
2008
Kif3a constrains β-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms
Primary cilia are microtubule-based organelles involved in signal transduction and project from the surface of most vertebrate… 
Review
2006
Review
2006
The roles of cilia in developmental disorders and disease
Cilia are highly conserved organelles that have diverse motility and sensory functions. Recent discoveries have revealed that… 
Highly Cited
2003
Highly Cited
2003
Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination
Nephronophthisis (NPHP), an autosomal recessive cystic kidney disease, leads to chronic renal failure in children. The genes… 
Highly Cited
2003
Highly Cited
2003
The left-right determinant Inversin is a component of node monocilia and other 9+0 cilia
Inversin (Inv), a protein that contains ankyrin repeats, plays a key role in left-right determination during mammalian embryonic… 
Highly Cited
2001
Highly Cited
2001
Olfactory receptor-gene clusters, genomic-inversion polymorphisms, and common chromosome rearrangements.
The olfactory receptor (OR)-gene superfamily is the largest in the mammalian genome. Several of the human OR genes appear in… 
Highly Cited
1999
Highly Cited
1999
Abnormal nodal flow precedes situs inversus in iv and inv mice.
Highly Cited
1999
Highly Cited
1999
BUGS in Bayesian stock assessments
This paper illustrates the ease with which Bayesian nonlinear state-space models can now be used for practical fisheries stock… 
Highly Cited
1998
Highly Cited
1998
Cloning of inv, a gene that controls left/right asymmetry and kidney development
Most vertebrate internal organs show a distinctive left/right asymmetry. The inv (inversion of embryonic turning) mutation in… 
Highly Cited
1997
Highly Cited
1997
Invasin-dependent and invasin-independent pathways for translocation of Yersinia pseudotuberculosis across the Peyer's patch intestinal epithelium
Yersinia pseudotuberculosis initiates systemic disease after translocation across the intestinal epithelium. Three Y… 
Highly Cited
1989
Highly Cited
1989
The ail locus is found uniquely in Yersinia enterocolitica serotypes commonly associated with disease
Yersinia enterocolitica is a heterogeneous group of organisms with more than 50 serotypes and several biotypes. Only a few of… 
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