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INS-365

Known as: INS 365, INS365 
 
National Institutes of Health

Papers overview

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2013
2013
  • R. Moss
  • The Journal of pediatrics
  • 2013
  • Corpus ID: 264741
T he life-shortening genetic disease cystic fibrosis (CF) is caused by mutations in the CF gene on both alleles, resulting in… Expand
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2007
2007
Extracellular nucleotides regulate ion transport and mucociliary clearance in human airway epithelial cells (HAECs) via the… Expand
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2005
2005
The most important risk factor for the development of glaucoma is elevated intraocular pressure (IOP). Hypotensive drugs decrease… Expand
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Highly Cited
2004
Highly Cited
2004
Purpose: To investigate the safety and efficacy of diquafosol tetrasodium, a P2Y2 receptor agonist that stimulates fluid and… Expand
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Highly Cited
2002
Highly Cited
2002
P2Y2 receptor agonists, like UTP and ATP, stimulate mucin secretion from goblet cells in vitro. Therefore, mucin stimulants could… Expand
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Highly Cited
2001
Highly Cited
2001
PURPOSE Because purinoceptor P2Y(2) receptor agonists elicit increases in net Cl, fluid transport, and glycoprotein release onto… Expand
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Highly Cited
2001
Highly Cited
2001
Rabbit conjunctival epithelium exhibits UTP-dependent Cl(-) secretion into the tears. We investigated whether fluid secretion… Expand
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2001
2001
Nucleotide agonists of P2Y2 receptors are potentially useful therapeutics for treating respiratory diseases such as chronic… Expand
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2001
2001
The purpose of this study was to evaluate the ocular safety and tolerability of the P2Y(2) receptor agonist, INS365, when applied… Expand
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1999
1999
The purpose of this study was to determine whether aerosolized INS316 (UTP) stimulates lung mucociliary clearance (MCC) in sheep… Expand
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