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INS-365

Known as: INS 365, INS365 
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
Extracellular nucleotides regulate ion transport and mucociliary clearance in human airway epithelial cells (HAECs) via the… 
2005
2005
The most important risk factor for the development of glaucoma is elevated intraocular pressure (IOP). Hypotensive drugs decrease… 
Highly Cited
2004
Highly Cited
2004
Purpose: To investigate the safety and efficacy of diquafosol tetrasodium, a P2Y2 receptor agonist that stimulates fluid and… 
Review
2004
Review
2004
The ophthalmic formulation of diquafosol tetrasodium (INS365), a P2Y2 receptor agonist, is targeted to treat dry eye disease… 
Highly Cited
2002
Highly Cited
2002
P2Y2 receptor agonists, like UTP and ATP, stimulate mucin secretion from goblet cells in vitro. Therefore, mucin stimulants could… 
Review
2002
Review
2002
Chronic bronchitis is in part characterized by mucus hypersecretion and the inability to clear airways of mucus. Despite years of… 
Highly Cited
2001
Highly Cited
2001
PURPOSE Because purinoceptor P2Y(2) receptor agonists elicit increases in net Cl, fluid transport, and glycoprotein release onto… 
Highly Cited
2001
Highly Cited
2001
Rabbit conjunctival epithelium exhibits UTP-dependent Cl(-) secretion into the tears. We investigated whether fluid secretion… 
1999
1999
The purpose of this study was to determine whether aerosolized INS316 (UTP) stimulates lung mucociliary clearance (MCC) in sheep…