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INHA gene

Known as: INHA, INHIBIN, ALPHA, inhibin alpha 
This gene plays a role in negatively regulating stromal cell proliferation in the gonads. It is also involved in cell growth and differentiation.
National Institutes of Health

Related topics

Related topics

5 relations
Cell Proliferation Regulatory ProcessINHA protein, humanIntercellular Communication ProcessRecombinant Inhibin A

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Mutational analysis of FOXL2 codon 134 in granulosa cell tumour of ovary and other human cancers
A missense somatic mutation in the FOXL2 gene affecting codon 134 has recently been reported in granulosa cell tumour (GCT) and… 
Highly Cited
2002
Highly Cited
2002
Mutation analysis of the inhibin alpha gene in a cohort of Italian women affected by ovarian failure.
BACKGROUND Premature ovarian failure (POF) is a secondary hypergonadotrophic amenorrhoea affecting 1-3% of females, whose… 
Highly Cited
2002
Highly Cited
2002
Alterations in Peripheral Concentrations of Inhibin A in Cattle Studied Using a Time-Resolved Immunofluorometric Assay: Relationship with Estradiol and Follicle-Stimulating Hormone in Various…
Abstract The aims of this study were to develop a sensitive and specific assay for bovine inhibin A using europium and to… 
Highly Cited
2001
Highly Cited
2001
Follicle-stimulating Hormone Stimulates Protein Kinase A-mediated Histone H3 Phosphorylation and Acetylation Leading to Select Gene Activation in Ovarian Granulosa Cells*
We examined the phosphorylation and acetylation of histone H3 in ovarian granulosa cells stimulated to differentiate by follicle… 
Highly Cited
2000
Highly Cited
2000
Follistatin is a modulator of gonadal tumor progression and the activin-induced wasting syndrome in inhibin-deficient mice.
Inhibins and activins are dimeric proteins belonging to the transforming growth factor-beta superfamily. Follistatin is an… 
Highly Cited
1998
Highly Cited
1998
Gonadotropins regulate inducible cyclic adenosine 3',5'-monophosphate early repressor in the rat ovary: implications for inhibin alpha subunit gene expression.
Many hormones that stimulate intracellular signaling pathways utilizing the second messenger cAMP affect gene expression in… 
Highly Cited
1996
Highly Cited
1996
Gonadectomy permits adrenocortical tumorigenesis in mice transgenic for the mouse inhibin alpha-subunit promoter/simian virus 40 T-antigen fusion gene: evidence for negative autoregulation of the…
We have developed a transgenic (TG) mouse model for gonadal tumorigenesis expressing the Simian virus 40 T-antigen (Tag) under… 
Highly Cited
1995
Highly Cited
1995
Gonadal tumorigenesis in transgenic mice bearing the mouse inhibin alpha-subunit promoter/simian virus T-antigen fusion gene: characterization of ovarian tumors and establishment of gonadotropin…
To establish in vivo gonadal tumor models and permanent lines of gonadal somatic cells we produced transgenic (TG) mice… 
Highly Cited
1989
Highly Cited
1989
Inhibin alpha-subunit monomer is present in bovine follicular fluid.
Highly Cited
1988
Highly Cited
1988
Gonadal and extragonadal expression of inhibin alpha, beta A, and beta B subunits in various tissues predicts diverse functions.
The S1-nuclease analysis was used to investigate the pattern of inhibin expression in the rat. In a first series of experiments… 
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