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INCB3344

 
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Macrophages accumulate in blood vessels during hypertension. However, their contribution to vessel remodeling is unknown. In the… Expand
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Highly Cited
2015
Highly Cited
2015
Background and Purpose— Ly6Chi monocytes are generally thought to exert a proinflammatory role in acute tissue injury, although… Expand
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2014
2014
Chemokine (C‐C motif) ligand 2 (CCL2) participates in different mechanisms contributing to the spinal cord inflammation and pain… Expand
2013
2013
The chemokine receptor CCR2 is a G protein–coupled receptor that is activated primarily by the endogenous CC chemokine ligand 2… Expand
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Highly Cited
2012
Highly Cited
2012
Infiltration of macrophages into the artery wall plays detrimental roles during hypertension by promoting vascular inflammation… Expand
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2011
2011
Purpose To investigate the effect of an intravitreally administered CCR2 antagonist, INCB3344, on a mouse model of choroidal… Expand
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Highly Cited
2011
Highly Cited
2011
Changes in function of voltage-gated sodium channels in nociceptive primary sensory neurons participate in the development of… Expand
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2010
2010
Rational design based on a pharmacophore of CCR2 antagonists reported in the literature identified lead compound 9a with potent… Expand
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2009
2009
The chemokine receptor 2 (CCR2) directs migration of monocytes and has been proposed to be a drug target for chronic inflammatory… Expand
Highly Cited
2005
Highly Cited
2005
This report describes the characterization of INCB3344, a novel, potent and selective small molecule antagonist of the mouse CCR2… Expand
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