INCB018424

Known as: INCB18424, Oral JAK Inhibitor INCB18424, INCB-018424 
 

Topic mentions per year

Topic mentions per year

2008-2016
051020082016

Papers overview

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2014
2014
and O Hantschel Department of Biochemistry, University of Zürich, Zürich, Switzerland; Swiss Institute for Experimental Cancer… (More)
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2011
2011
INCB018424 phosphate, a potent inhibitor of JAK enzymes with selectivity for JAK1&2, is in development for the treatment of… (More)
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2011
2011
BACKGROUND Symptomatic burden from constitutional symptoms, anemia, and splenomegaly-related symptoms are common and morbidity… (More)
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2011
2011
Myeloma cells are dependent on IL6 for their survival and proliferation during the early stages of disease, and independence from… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Myelofibrosis is a Philadelphia chromosome–negative myeloproliferative neoplasm associated with cytopenias… (More)
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Highly Cited
2010
Highly Cited
2010
Constitutive JAK2 activation in hematopoietic cells by the JAK2V617F mutation recapitulates myeloproliferative neoplasm (MPN… (More)
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2010
2010
Ruxolitinib (INCB-018424) is a potent, orally available, selective inhibitor of both JAK1 and JAK2 of the JAK-STAT signaling… (More)
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2010
2010
The metabolism, excretion, and pharmacokinetics of 3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3… (More)
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Highly Cited
2010
Highly Cited
2010
Inhibiting signal transduction induced by inflammatory cytokines offers a new approach for the treatment of autoimmune diseases… (More)
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2009
2009
An enantioselective synthesis of INCB018424 via organocatalytic asymmetric aza-Michael addition of pyrazoles (16 or 20) to (E)-3… (More)
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