FAQ

IL34 gene

Known as: Interleukin 34 Gene, MGC34647, INTERLEUKIN 34 
This gene plays a role in receptor binding and cytokine-dependent signaling.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2009-2017
05101520092017

Related topics

Related topics

7 relations
Cell Proliferation Regulatory ProcessCytokine Receptor BindingCytokine SignalingImmune Cell Activation Process
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Related mentions per year

Related mentions per year

1937-2018
19401960198020002020
IL34 gene
inflammatory response
Intercellular Communication Process
Immune Cell Activation Process
Cell Proliferation Regulatory Process
Cytokine Signaling

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
IL-34 is associated with obesity, chronic inflammation, and insulin resistance.
OBJECTIVES IL-34 is a recently identified alternative ligand for colony-stimulating factor-1 (CSF-1) receptor. IL-34 and CSF-1… (More)
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2013
2013
Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival
Colony-stimulating factor 1 (CSF1) and interleukin-34 (IL-34) are functional ligands of the CSF1 receptor (CSF1R) and thus are… (More)
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2013
2013
IL-34 is overexpressed in the inflamed salivary glands of patients with Sjogren's syndrome and is associated with the local expansion of pro-inflammatory CD14(bright)CD16+ monocytes.
OBJECTIVES To investigate the expression of IL-34 in labial salivary glands (LSGs) of patients with primary SS (p-SS) and its… (More)
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2013
2013
Increased levels of interleukin 34 in serum and synovial fluid are associated with rheumatoid factor and anticyclic citrullinated peptide antibody titers in patients with rheumatoid arthritis.
OBJECTIVE Interleukin 34 (IL-34) is a recently discovered cytokine that binds macrophage colony-stimulating factor (M-CSF… (More)
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2013
2013
Transcriptional profiling and pathway analysis of CSF-1 and IL-34 effects on human monocyte differentiation.
CSF-1 is the well-known ligand for CSF-1R, which plays a vital role in monocyte-macrophage generation, survival, and function. IL… (More)
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Highly Cited
2012
Highly Cited
2012
IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia
The differentiation of bone marrow–derived progenitor cells into monocytes, tissue macrophages and some dendritic cell (DC… (More)
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2011
2011
Interleukin-34 selectively enhances the neuroprotective effects of microglia to attenuate oligomeric amyloid-β neurotoxicity.
Microglia, macrophage-like resident immune cells in the brain, possess both neurotoxic and neuroprotective properties and have a… (More)
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2010
2010
Pivotal Advance: Avian colony-stimulating factor 1 (CSF-1), interleukin-34 (IL-34), and CSF-1 receptor genes and gene products.
Macrophages are involved in many aspects of development, host defense, pathology, and homeostasis. Their normal differentiation… (More)
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Highly Cited
2010
Highly Cited
2010
Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells.
CSF-1 is broadly expressed and regulates macrophage and osteoclast development. The action and expression of IL-34, a novel CSF… (More)
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2010
2010
Macrophage-colony stimulating factor and interleukin-34 induce chemokines in human whole blood.
The aim of this study is to investigate if macrophage-colony stimulating factor (M-CSF) or interleukin-34 (IL-34) induces… (More)
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