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IL21 wt Allele

Known as: IL-21, Interleukin 21 wt Allele, Za11 
Human IL21 wild-type allele is located within 4q26-q27 and is approximately 8 kb in length. This allele, which encodes interleukin-21 protein, is… 
National Institutes of Health

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4q26-q27Cell Proliferation Regulatory ProcessCell-Mediated CytolysisCytokine Receptor Binding

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interleukin-21

Papers overview

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2014
2014
The effect of aging on the frequency, phenotype and cytokine production of human blood CD4 + CXCR5 + T follicular helper cells: comparison of aged and young subjects
BackgroundT cell-dependent B-cell responses decline with age, indicating declined cognate helper activity of aged CD4 + T cells… 
2014
2014
Effects of IL-21, KIR Blockade, and CD137 Agonism on the Non-Clinical Activity of Elotuzumab
Elotuzumab is a humanized monoclonal antibody (mAb) that binds specifically to Signaling Lymphocytic Activation Molecule F7… 
2013
2013
IL-21 R gene polymorphisms and serum IL-21 levels predict virological response to interferon-based therapy in Asian chronic hepatitis C patients
Background: IL-21R polymorphisms have been identified as potential predictors of virological outcomes in Western chronic… 
2013
2013
Serum Levels of IL-21 and TGF-β in the Yusho Patients
Aryl hydrocarbonreceptor (AhR), recogn ized as a dioxinreceptor, is expressed onthe surface of helper T (Th) 17 cells .A s PCBs… 
2013
2013
[Serum levels of IL-21 and TGF-beta in the Yusho patients].
Aryl hydrocarbon receptor (AhR), recognized as a dioxin receptor, is expressed on the surface of helper T (Th) 17 cells. As PCBs… 
2012
2012
Tumor Necrosis Factor Blockade Differentially Affects Innate Inflammatory and Th17 Cytokines in Rheumatoid Arthritis
Objective. To evaluate the effect of a tumor necrosis factor-α (TNF-α) inhibitor (etanercept) on innate inflammatory and Th17… 
2011
2011
Interleukin-21 in hemodialyzed patients: association with the etiology of chronic kidney disease and the seropositivity against hepatitis C virus infection.
2011
2011
IL-21 level in Chinese HIV infected individuals and its dynamics undergoing HAART.
OBJECTIVE To investigate the dynamics of interleukin-21(IL-21) cytokine in the Chinese HIV patients undergoing highly active… 
2008
2008
IL‐21 and autoimmune disease – hypothesis and reality?
Previous data have indicated that IL‐21 and/or IL‐21R are crucial for the differentiation of naïve T cells into Th17 cells and… 
2007
2007
[Serum IL-21 level in patients with primary Sjogren's syndrome and clinical significance of IL-21].
AIM To investigate the relation between the change of serum IL-21 level and other laboratory indexes by detecting serum IL-21… 
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