IL2 wt Allele

Known as: Aldesleukin Gene, T Cell Growth Factor Gene, Interleukin 2 wt Allele 
Human IL2 wild-type allele is located within 4q26-q27 and is approximately 5 kb in length. This allele, which encodes interleukin-2 protein, plays a… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1981-2000
02419812000

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1993
1993
The immunosuppressive drugs cyclosporin A (CsA) and FK506 bind to distinct families of intracellular proteins, cyclophilins, and… (More)
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1993
1993
Cyclosporin A and the macrolide tacrolimus (FK506) are powerful immunosuppressive drugs that in T cells inhibit the calcium… (More)
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Highly Cited
1992
Highly Cited
1992
ANTIGEN recognition by the T-cell receptor (TCR) initiates events including lymphokine gene transcription1, particularly… (More)
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1992
1992
Effective vaccination against cancer, either for prophylaxis or therapy, has been an elusive goal for years. Cytokine gene… (More)
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1992
1992
CD4+ T cells were separated into subpopulations according to their expression of different isoforms of the CD45R molecule, i.e… (More)
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Highly Cited
1991
Highly Cited
1991
A simple in vitro experimental system was devised to reflect the in vivo generation of a T cell anamnestic response so that T… (More)
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1990
1990
We have reported recently that high concentrations of anti-CD3 mAb inhibited IL-2-dependent proliferation of TH1 but not TH2… (More)
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1990
1990
Common variable immunodeficiency (CVI) is a syndrome characterized by hypogammaglobulinemia, recurrent bacterial infections, and… (More)
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1990
1990
The kinetics of lymphokine RNA induction and secretion of biologically active lymphokine from CD4-enriched splenic T cell… (More)
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Highly Cited
1988
Highly Cited
1988
  • BY W. HENRY BOOM, DOUGLAS LIANO, A. Abbas
  • 1988
Murine class II MHC-restricted helper/inducer T lymphocytes can be divided into at least two nonoverlapping subsets, based on… (More)
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