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IL-10 Immunomodulator MK-1966
Known as:
MK 1966
, MK-1966
An agent that downregulates the activity of the anti-inflammatory cytokine human interleukin-10 (IL-10), with potential immunomodulating and…
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National Institutes of Health
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Papers overview
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2006
2006
Mesangial cells initiate compensatory renal tubular hypertrophy via IL-10-induced TGF-beta secretion: effect of the immunomodulator AS101 on this process.
I. Sinuani
,
Z. Averbukh
,
+5 authors
J. Weissgarten
AJP - Renal Physiology
2006
Corpus ID: 6440863
The present study investigated the role of IL-10 produced by the mesangial cells in postnephrectomy compensatory renal growth and…
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2006
2006
Retracted: Fat‐Derived Hormone Adiponectin Combined with FTY720 Significantly Improves Small‐for‐Size Fatty Liver Graft Survival
K. Man
,
Y. Zhao
,
+8 authors
S. Fan
American Journal of Transplantation
2006
Corpus ID: 34323307
Owing to the discrepancy between organ donation and the demand for liver transplantation, expanding the liver donor pool is of…
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2000
2000
Linomide abolishes leukocyte adhesion and extravascular recruitment induced by tumor necrosis factor α in vivo
X. Zhang
,
G. Hedlund
,
P. Borgström
,
K. Arfors
,
H. Thorlacius
Journal of Leukocyte Biology
2000
Corpus ID: 21985793
The immunomodulator Linomide (roquinimex) ameliorates the development of numerous inflammatory and immunological diseases…
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Highly Cited
1997
Highly Cited
1997
Delay in the onset of systemic lupus erythematosus following treatment with the immunomodulator AS101: association with IL-10 inhibition and increase in TNF-alpha levels.
Y. Kalechman
,
U. Gafter
,
J. Da
,
M. Albeck
,
D. Alarcón-Segovia
,
B. Sredni
Journal of Immunology
1997
Corpus ID: 38251556
It has recently been found that in systemic lupus erythematosus (SLE), a multisystem inflammatory disorder characterized by…
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Highly Cited
1996
Highly Cited
1996
The protective role of the immunomodulator AS101 against chemotherapy‐induced alopecia studies on human and animal models
B. Sredni
,
R. Xu
,
+11 authors
Y. Kalechman
International Journal of Cancer
1996
Corpus ID: 23365813
The immunomodulator AS101 has been demonstrated to exhibit radioprotective and chemoprotective effects in mice. Following phase‐I…
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1996
1996
Antibabesial effect of the immunomodulator AS101 in mice: role of increased production of nitric oxide
H. Rosenblatt-Bin
,
A. Klein
,
B. Sredni
Parasite immunology (Print)
1996
Corpus ID: 24318314
The immunomodulator AS101 has been shown to induce cell proliferation and to increase the secretion of a variety of cytokines. In…
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1994
1994
Restoration of murine cytomegalovirus (MCMV) induced myelosuppression by AS101.
B. Sredni
,
Z. Rosenthal-Galili
,
+5 authors
B. Rager-Zisman
Immunology Letters
1994
Corpus ID: 3432913
Highly Cited
1992
Highly Cited
1992
The immunomodulator AS101 administered orally as a chemoprotective and radioprotective agent.
B. Sredni
,
M. Albeck
,
G. Kazimirsky
,
F. Shalit
International Journal of Immunopharmacology
1992
Corpus ID: 24358305
1991
1991
Transplantation of Purified Islet Cells in Diabetic Rats: III. Immunosuppressive Effect of Cyclosporin
M. Pipeleers-Marichal
,
Z. Ling
,
H. Teng
,
D. Pipeleers
Diabetes
1991
Corpus ID: 36829331
This study examined the effect of cyclosporin on the survival of islet β-cell allografts in streptozocin (STZ)-induced diabetic…
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1990
1990
The effect of the immunomodulator agent AS101 on interleukin‐2 production in systemic lupus erythematosus (SLE) induced in mice by a pathogenic anti‐DNA antibody
M. Blank
,
B. Sredni
,
M. Albeck
,
E. Mozes
,
Y. Shoenfeld
Clinical and Experimental Immunology
1990
Corpus ID: 11788462
The role of the synthetic immunomodulator AS101 on the production of interleukin‐2 (IL‐2) by spleen cells of mice with SLE was…
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