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IKBKAP gene

Known as: elongator acetyltransferase complex subunit 1, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein, ELP1 
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Patient-specific induced pluripotent stem cells (iPSCs) represent a novel system for modeling human genetic disease and could… Expand
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Highly Cited
2008
Highly Cited
2008
ABSTRACT Familial dysautonomia (FD), a devastating hereditary sensory and autonomic neuropathy, results from an intronic mutation… Expand
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Highly Cited
2005
Highly Cited
2005
The activation of Rab GTPases is a critical focal point of membrane trafficking events in eukaryotic cells; however, the cellular… Expand
Highly Cited
2002
Highly Cited
2002
ABSTRACT To physically characterize the web of interactions connecting the Saccharomyces cerevisiae proteins suspected to be RNA… Expand
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Highly Cited
2002
Highly Cited
2002
Human Elongator complex was purified to virtual homogeneity from HeLa cell extracts. The purified factor can exist in two forms… Expand
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Highly Cited
2001
Highly Cited
2001
Familial dysautonomia (FD; also known as "Riley-Day syndrome"), an Ashkenazi Jewish disorder, is the best known and most frequent… Expand
Highly Cited
2001
Highly Cited
2001
ABSTRACT The Elongator complex associated with elongating RNA polymerase II in Saccharomyces cerevisiae was originally reported… Expand
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Highly Cited
2001
Highly Cited
2001
Elongator is a histone acetyltransferase complex that associates with the elongating form of RNA polymerase II. We purified… Expand
Highly Cited
2000
Highly Cited
2000
A critical step in the activation of NF-κB is the phosphorylation of IκBs by the IκB kinase (IKK) complex. IKKα and IKKβ are the… Expand
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Highly Cited
1999
Highly Cited
1999
One mechanism leading to neurodegeneration during Alzheimer's disease (AD) is amyloid beta peptide (Abeta) neurotoxicity. Abeta… Expand
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