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IKBKAP gene

Known as: elongator acetyltransferase complex subunit 1, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein, ELP1 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Ikbkap/Elp1 Deficiency Causes Male Infertility by Disrupting Meiotic Progression
Mouse Ikbkap gene encodes IKAP—one of the core subunits of Elongator—and is thought to be involved in transcription. However, the… 
2013
2013
Phosphatidylserine increases IKBKAP levels in a humanized knock-in IKBKAP mouse model.
Familial dysautonomia (FD) is a severe neurodegenerative genetic disorder restricted to the Ashkenazi Jewish population. The most… 
2010
2010
Phosphatidylserine Increases IKBKAP Levels in Familial Dysautonomia Cells
Familial Dysautonomia (FD) is an autosomal recessive congenital neuropathy that results from abnormal development and progressive… 
Highly Cited
2009
Highly Cited
2009
Elongator function depends on antagonistic regulation by casein kinase Hrr25 and protein phosphatase Sit4
In yeast, the role for the Elongator complex in tRNA anticodon modification is affected by phosphorylation of Elongator subunit… 
Highly Cited
2006
Highly Cited
2006
Tumor accumulation, degradation and pharmacokinetics of elastin-like polypeptides in nude mice.
2005
2005
Tocotrienols reverse IKAP and monoamine oxidase deficiencies in familial dysautonomia.
Highly Cited
2003
Highly Cited
2003
The yeast elongator histone acetylase requires Sit4-dependent dephosphorylation for toxin-target capacity.
Kluyveromyces lactis zymocin, a heterotrimeric toxin complex, imposes a G1 cell cycle block on Saccharomyces cerevisiae that… 
2002
2002
Protein interactions within Saccharomyces cerevisiae Elongator, a complex essential for Kluyveromyces lactis zymocicity
mTn3‐tagging identified Kluyveromyces lactis zymocin target genes from Saccharomyces cerevisiae as TOT1–3/ELP1–3 coding for the… 
2001
2001
Cloning, characterization, and genomic structure of the mouse Ikbkap gene.
Our laboratory recently reported that mutations in the human I-kappaB kinase-associated protein (IKBKAP) gene are responsible for… 
1997
1997
Characterization of IKI1 and IKI3 genes conferring pGKL killer sensitivity on Saccharomyces cerevisiae.
The Saccharomyces cerevisiae iki mutants show an insensitive phenotype to the pGKL killer toxin, and we have cloned some IKI… 
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