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IFNL3 gene

Known as: interferon, lambda 3, INTERLEUKIN 28B, Interferon, Lambda 3 Gene 
This gene plays a role in cytokine signaling.
National Institutes of Health

Related topics

Related topics

7 relations
Antiviral ResponseCytokine Receptor BindingCytokine SignalingIFNL1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Telaprevir can be successfully and safely used to treat older patients with genotype 1b chronic hepatitis C.
2012
2012
Insulin resistance undermines the advantages of IL28B polymorphism in the pegylated interferon alpha-2b and ribavirin treatment of chronic hepatitis C patients with genotype 1.
2012
2012
Genetic variation in IL28B and treatment outcome in HBeAg-positive and -negative chronic hepatitis B patients treated with Peg interferon alfa-2a and adefovir
Abstract In a cohort of 95 chronic hepatitis B patients, who were treated with peg-interferon and adefovir for 1 year, and who… 
2012
2012
Impact of IL28B-Related Single Nucleotide Polymorphisms on Liver Histopathology in Chronic Hepatitis C Genotype 2 and 3
Background and Aims Recently, several genome-wide association studies have revealed that single nucleotide polymorphisms (SNPs… 
2012
2012
Distribution of IL28B Genotypes in Iranian Patients with Chronic Hepatitis C and Healthy Individuals
Background IL28B polymorphism is recognized as one of the most prominent predictors of hepatitis C spontaneous and treatment… 
Highly Cited
2011
Highly Cited
2011
IL28B genetic variation and treatment response in patients with hepatitis C virus genotype 3 infection
Polymorphisms near the IL28B gene, which code for interferon (IFN)‐λ3, predict response to pegylated interferon‐α (PEG‐IFN) and… 
Highly Cited
2011
Highly Cited
2011
Genetic variation in IL28B and treatment-induced clearance of hepatitis C virus in HIV-positive patients with acute and chronic hepatitis C.
Recently, a IL28B (rs 12979860) gene polymorphism was identified as a predictor for response to hepatitis C virus-specific… 
2011
2011
Importance of Host Genetic Factors HLA and IL28B as Predictors of Response to Pegylated Interferon and Ribavirin
OBJECTIVES:Viral factors are considered the best predictors of response to treatment for chronic hepatitis C (CHC), but genetic… 
2011
2011
Association of IL28B variants with response to pegylated‐interferon alpha plus ribavirin combination therapy reveals intersubgenotypic differences between genotypes 2a and 2b
Genetic polymorphisms of the interleukin 28B (IL28B) locus are associated closely with outcomes of pegylated‐interferon (PEG‐IFN… 
2011
2011
Association of Genetic Variation in Il28B with Hepatitis C Treatment-Induced Viral Clearance in the Chinese Han Population
Background Genome-wide association studies have recently shown that the rs12979860 polymorphism in IL28B is associated with the… 
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