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IFNGR1 wt Allele

Known as: Antiviral Protein, Type 2 Gene, IMD27B, IFNGR 
Human IFNGR1 wild-type allele is located within 6q23-q24 and is approximately 22 kb in length. This allele, which encodes interferon gamma receptor 1… Expand
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Immune interferon (IFN), also known as IFN-γ, promotes not only immunomodulation but also antimicrobial and anticancer activity… Expand
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Review
2014
Review
2014
The mammalian taste bud is an onion-shaped epithelial structure with 50-100 tightly packed cells, including taste receptor cells… Expand
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Highly Cited
2010
Highly Cited
2010
Autocrine priming of cells by small quantities of constitutively produced type I interferon (IFN) is a well-known phenomenon. In… Expand
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Highly Cited
2010
Highly Cited
2010
Production of type I interferon (IFN; IFN-alphabeta) increases host susceptibility to Listeria monocytogenes, whereas type II IFN… Expand
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Highly Cited
2007
Highly Cited
2007
BackgroundTo gain insight into host-microbe interactions in a piglet model, a functional genomics approach was used to address… Expand
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Highly Cited
2007
Highly Cited
2007
We have documented the key role of toll-like receptor 4 (TLR4) activation and its signaling pathway mediated by interferon (IFN… Expand
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2006
2006
Interferon-gamma (IFN-gamma) induces the enzyme indoleamine dioxygenase (IDO) in a variety of human cell types. Furthermore… Expand
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Highly Cited
2004
Highly Cited
2004
Activation of the naive T-helper lymphocyte (Thp) directs it down one of two major developmental pathways called Th1 and Th2… Expand
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Highly Cited
2004
Highly Cited
2004
Summary Background Interferon γ receptor 1 (IFNγ R1) deficiency is a primary immunodeficiency with allelic dominant and recessive… Expand
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Highly Cited
2003
Highly Cited
2003
Interferon-gamma (IFN-gamma)-induced indoleamine 2,3-dioxygenase (IDO) activity inhibits the growth of susceptible intracellular… Expand
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