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IFNGR1 wt Allele

Known as: Antiviral Protein, Type 2 Gene, IMD27B, IFNGR 
Human IFNGR1 wild-type allele is located within 6q23-q24 and is approximately 22 kb in length. This allele, which encodes interferon gamma receptor 1… Expand
National Institutes of Health

Related topics

Related topics

12 relations
6q23-q24Antiviral ResponseCytokine Signaling ProcessHelicobacter pylori infection
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Taste bud homeostasis in health, disease, and aging.
The mammalian taste bud is an onion-shaped epithelial structure with 50-100 tightly packed cells, including taste receptor cells… Expand
Highly Cited
2010
Highly Cited
2010
Induction of IFN-αβ enables Listeria monocytogenes to suppress macrophage activation by IFN-γ
Production of type I interferon (IFN; IFN-αβ) increases host susceptibility to Listeria monocytogenes, whereas type II IFN (IFN… Expand
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Highly Cited
2010
Highly Cited
2010
Functional Crosstalk between Type I and II Interferon through the Regulated Expression of STAT1
Small "priming" quantities of type I interferon enhance cellular responses to type II interferon by maintaining basal levels of… Expand
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Highly Cited
2008
Highly Cited
2008
Type I, but not type II, interferon is critical in liver injury induced after ischemia and reperfusion
We have documented the key role of toll‐like receptor 4 (TLR4) activation and its signaling pathway mediated by interferon (IFN… Expand
Highly Cited
2007
Highly Cited
2007
Transcriptome profiling of the small intestinal epithelium in germfree versus conventional piglets
BackgroundTo gain insight into host-microbe interactions in a piglet model, a functional genomics approach was used to address… Expand
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Highly Cited
2006
Highly Cited
2006
Upregulation of IFN-gamma receptor expression by proinflammatory cytokines influences IDO activation in epithelial cells.
Interferon-gamma (IFN-gamma) induces the enzyme indoleamine dioxygenase (IDO) in a variety of human cell types. Furthermore… Expand
Highly Cited
2004
Highly Cited
2004
Clinical features of dominant and recessive interferon γ receptor 1 deficiencies
BACKGROUND Interferon gamma receptor 1 (IFNgammaR1) deficiency is a primary immunodeficiency with allelic dominant and… Expand
Highly Cited
2004
Highly Cited
2004
A role for the immunological synapse in lineage commitment of CD4 lymphocytes
Activation of the naive T-helper lymphocyte (Thp) directs it down one of two major developmental pathways called Th1 and Th2… Expand
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Highly Cited
2003
Highly Cited
2003
Synergistic transcriptional activation of indoleamine dioxygenase by IFN-gamma and tumor necrosis factor-alpha.
Interferon-gamma (IFN-gamma)-induced indoleamine 2,3-dioxygenase (IDO) activity inhibits the growth of susceptible intracellular… Expand
1999
1999
Dietary omega-3 polyunsaturated fatty acids reduce IFN-gamma receptor expression in mice.
Enrichment of immune cells in vivo or in vitro with omega-3 polyunsaturated fatty acid (n-3 PUFA) has been reported to diminish… Expand
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