FAQ

IFNGR1 wt Allele

Known as: Antiviral Protein, Type 2 Gene, IMD27B, IFNGR 
Human IFNGR1 wild-type allele is located within 6q23-q24 and is approximately 22 kb in length. This allele, which encodes interferon gamma receptor 1… (More)

Topic mentions per year

Topic mentions per year

1999-2017
02419992017

Related topics

Related topics

10 relations
6q23-q24Antiviral ResponseCytokine Signaling ProcessHelicobacter pylori infection
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
IFNGR1 wt Allele
Tuberculosis
Helicobacter pylori infection
Intercellular Communication Process
Mycobacterium Infections
Antiviral Response

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Type I IFNs downregulate myeloid cell IFN-γ receptor by inducing recruitment of an early growth response 3/NGFI-A binding protein 1 complex that silences ifngr1 transcription.
The ability of type I IFNs to increase susceptibility to certain bacterial infections correlates with downregulation of myeloid… (More)
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2009
2009
Interferon-gamma-dependent cytotoxic activation of human astrocytes and astrocytoma cells.
Astrocytes and microglia become activated in a broad spectrum of inflammatory neurodegenerative diseases. Activated microglia are… (More)
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2009
2009
Control of T helper cell differentiation through cytokine receptor inclusion in the immunological synapse
The antigen recognition interface formed by T helper precursors (Thps) and antigen-presenting cells (APCs), called the… (More)
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2008
2008
Type I, but not type II, interferon is critical in liver injury induced after ischemia and reperfusion.
We have documented the key role of toll-like receptor 4 (TLR4) activation and its signaling pathway mediated by interferon (IFN… (More)
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2008
2008
Negative feedback regulation of IFN-gamma pathway by IFN regulatory factor 2 in esophageal cancers.
IFN-gamma is an antitumor cytokine that inhibits cell proliferation and induces apoptosis after engagement with the IFN-gamma… (More)
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2007
2007
Transcriptome profiling of the small intestinal epithelium in germfree versus conventional piglets
To gain insight into host-microbe interactions in a piglet model, a functional genomics approach was used to address the working… (More)
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Highly Cited
2004
Highly Cited
2004
A role for the immunological synapse in lineage commitment of CD4 lymphocytes.
Activation of the naive T-helper lymphocyte (Thp) directs it down one of two major developmental pathways called Th1 and Th2… (More)
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2003
2003
A novel single-nucleotide substitution, Leu 467 Pro, in the interferon-gamma receptor 1 gene associated with allergic diseases.
We identified a novel heterozygous single-nucleotide substitution 1400 T right curved arrow C (Leu 467 Pro) in the seventh exon… (More)
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2001
2001
Mouse oocytes and preimplantation embryos bear the two sub-units of interferon-gamma receptor.
Cytokines and growth factors play important roles in implantation and maintenance of pregnancy, but also during early development… (More)
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1999
1999
Dietary omega-3 polyunsaturated fatty acids reduce IFN-gamma receptor expression in mice.
Enrichment of immune cells in vivo or in vitro with omega-3 polyunsaturated fatty acid (n-3 PUFA) has been reported to diminish… (More)
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