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IFNAR1 gene

Known as: IFNBR, IFNAR, IFRC INTERFERON-BETA RECEPTOR 
This gene is involved in tyrosine-kinase signal transduction and receptor mediation.
National Institutes of Health

Related topics

Related topics

10 relations
Antiviral ResponseCytokine Signaling ProcessImmunityIntercellular Communication Process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Defining the distinct, intrinsic properties of the novel type I interferon, IFNϵ
The type I interferons (IFNs) are a family of cytokines with diverse biological activities, including antiviral… 
2007
2007
Comparable potency of IFNalpha2 and IFNbeta on immediate JAK/STAT activation but differential down-regulation of IFNAR2.
Type I IFNs (interferons) (IFNalpha/beta) form a family of related cytokines that control a variety of cellular functions through… 
2004
2004
Type I interferon receptor and response to interferon therapy in chronic hepatitis C patients: a prospective study
Summary.  The type I interferon (IFN) receptor consists of at least two subunits, IFNAR1 and IFNAR2. We previously found a… 
Highly Cited
2000
Highly Cited
2000
Interferon-dependent activation of the serine kinase PI 3'-kinase requires engagement of the IRS pathway but not the Stat pathway.
Several signaling pathways are activated by interferon alpha (IFNalpha) in hematopoietic cells, including the Jak-Stat and the… 
2000
2000
Expression of the Genes Encoding the Vasopressin‐Activated Calcium‐Mobilizing Receptor and the Dual Angiotensin II/Vasopressin Receptor in the Rat Central Nervous System
The distributions of two newly discovered receptors, the vasopressin‐activated calcium‐mobilizing receptor (VACM‐1) and the dual… 
1999
1999
Formation of a uniquely stable type I interferon receptor complex by interferon beta is dependent upon particular interactions between interferon beta and its receptor and independent of tyrosine…
Human type I interferons (IFN) require two receptor chains, IFNAR1 and IFNAR2c for high affinity (pM) binding and biological… 
Highly Cited
1998
Highly Cited
1998
Specific Contribution of Tyk2 JH Regions to the Binding and the Expression of the Interferon α/β Receptor Component IFNAR1*
Cytokine signaling involves the activation of the Janus kinase (JAK) family of tyrosine kinases. These enzymes are physically… 
Highly Cited
1997
Highly Cited
1997
Molecular cloning of ovine and bovine type I interferon receptor subunits from uteri, and endometrial expression of messenger ribonucleic acid for ovine receptors during the estrous cycle and…
Interferon-tau (IFN-tau), a type I IFN structurally related to IFN-alpha, is regarded as the major antiluteolytic factor secreted… 
Highly Cited
1993
Highly Cited
1993
Identification of a novel subunit of the type I interferon receptor localized to human chromosome 21.
1990
1990
Molecular analysis of autosomal dominant neurohypophyseal diabetes insipidus.
The status of the arginine vasopressin-neurophysin-II (AVP-NPII) gene was studied in three families with autosomal dominant… 
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