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IFNAR1 gene

Known as: IFNBR, IFNAR, IFRC INTERFERON-BETA RECEPTOR 
This gene is involved in tyrosine-kinase signal transduction and receptor mediation.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Type I interferons are important in regulating immune responses to pathogens and tumors. All interferons are considered to signal… Expand
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Highly Cited
2013
Highly Cited
2013
RATIONALE Patients who developed acute respiratory distress syndrome (ARDS) after infection with severe respiratory viruses (e.g… Expand
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Review
2011
Review
2011
Systemic lupus erythematosus (SLE) is a multifactorial autoimmune disorder. The study of diverse mouse models of lupus has… Expand
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Highly Cited
2011
Highly Cited
2011
Dendritic cell responsiveness to type I interferon is required for the generation of antitumor T cell responses and tumor… Expand
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Highly Cited
2011
Highly Cited
2011
Type I IFNs are critical players in host innate and adaptive immunity. IFN signaling is tightly controlled to ensure appropriate… Expand
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Highly Cited
2008
Highly Cited
2008
Tumor suppressor p53 is activated by several stimuli, including DNA damage and oncogenic stress. Previous studies (Takaoka, A., S… Expand
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Highly Cited
2007
Highly Cited
2007
Ligand-induced endocytosis and lysosomal degradation of cognate receptors regulate the extent of cell signaling. Along with… Expand
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Highly Cited
2004
Highly Cited
2004
Ubiquitination, endocytosis, and lysosomal degradation of the IFNAR1 (interferon α receptor 1) subunit of the type I interferon… Expand
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Highly Cited
2003
Highly Cited
2003
The four mammalian Jak tyrosine kinases are non-covalently associated with cell surface receptors binding helical bundled… Expand
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Highly Cited
1995
Highly Cited
1995
To examine the in vivo role(s) of type I interferons (IFNs) and to determine the role of a component of the type I IFN receptor… Expand
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