IFNAR1 gene

Known as: IFNBR, IFNAR, IFRC INTERFERON-BETA RECEPTOR 
This gene is involved in tyrosine-kinase signal transduction and receptor mediation.

Topic mentions per year

Topic mentions per year

1990-2018
0204019902018

Papers overview

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2007
2007
All alpha-interferons (IFNalpha) bind the IFNAR1 receptor subunit with low affinity. Increasing the binding affinity was shown to… (More)
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2006
Highly Cited
2006
Alpha and beta interferons (IFN-alpha and IFN-beta) are multifunctional cytokines that exhibit differential activities through a… (More)
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2003
Highly Cited
2003
The four mammalian Jak tyrosine kinases are non-covalently associated with cell surface receptors binding helical bundled… (More)
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2003
2003
The chromosome 21q22.11 cytokine receptor cluster contains four genes that encode subunits of the receptors for the cytokines… (More)
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2003
Highly Cited
2003
Down-regulation of activated signaling receptors in response to their ligands plays a key role in restricting the extent and… (More)
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2000
Highly Cited
2000
Definition of cellular responses to cytokines often involves cross-communication through their respective receptors. Here… (More)
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1998
Highly Cited
1998
BACKGROUND The interferons (IFNs) have been extensively studied in the context of host defence against viral infection. In the… (More)
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1997
1997
The intracytoplasmic domain (IC) of cytokine receptors provides docking sites for proteins which mediate signal transduction… (More)
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1997
Highly Cited
1997
STAT (signal transducers and activators of transcription) proteins undergo cytokine-dependent phosphorylation on serine and… (More)
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1995
Highly Cited
1995
To examine the in vivo role(s) of type I interferons (IFNs) and to determine the role of a component of the type I IFN receptor… (More)
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