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IFNAR1 gene

Known as: IFNBR, IFNAR, IFRC INTERFERON-BETA RECEPTOR 
This gene is involved in tyrosine-kinase signal transduction and receptor mediation.
National Institutes of Health

Related topics

Related topics

10 relations
Antiviral ResponseCytokine Signaling ProcessImmunityIntercellular Communication Process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Structural basis of a unique interferon-β signaling axis mediated via the receptor IFNAR1
Type I interferons are important in regulating immune responses to pathogens and tumors. All interferons are considered to signal… 
Highly Cited
2013
Highly Cited
2013
CXCL10-CXCR3 enhances the development of neutrophil-mediated fulminant lung injury of viral and nonviral origin.
RATIONALE Patients who developed acute respiratory distress syndrome (ARDS) after infection with severe respiratory viruses (e.g… 
Highly Cited
2011
Highly Cited
2011
Type I interferon is selectively required by dendritic cells for immune rejection of tumors
Dendritic cell responsiveness to type I interferon is required for the generation of antitumor T cell responses and tumor… 
Review
2011
Review
2011
Murine Models of Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a multifactorial autoimmune disorder. The study of diverse mouse models of lupus has… 
Highly Cited
2011
Highly Cited
2011
Structural Linkage between Ligand Discrimination and Receptor Activation by Type I Interferons
Highly Cited
2006
Highly Cited
2006
Resistance to Alpha/Beta Interferon Is a Determinant of West Nile Virus Replication Fitness and Virulence
ABSTRACT The emergence of West Nile virus (WNV) in the Western Hemisphere is marked by the spread of pathogenic lineage I strains… 
Review
1997
Review
1997
Jaks, STATs, cytokine signal transduction, and immunoregulation: are we there yet?
Highly Cited
1997
Highly Cited
1997
STAT3 as an adapter to couple phosphatidylinositol 3-kinase to the IFNAR1 chain of the type I interferon receptor.
STAT (signal transducers and activators of transcription) proteins undergo cytokine-dependent phosphorylation on serine and… 
Highly Cited
1997
Highly Cited
1997
Functional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signaling
Two members of the STAT signal transducer and activator of transcription family, STAT1 and STAT2, are rapidly phosphorylated on… 
Highly Cited
1995
Highly Cited
1995
Cloning and Expression of a Long Form of the β Subunit of the Interferon αβ Receptor That Is Required for Signaling (*)
The interferon αβ receptor (IFNαR) or type I IFN-R is formed by a 110-kDa α subunit or IFNAR and by a β subunit, which has short… 
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