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ICT2700

National Institutes of Health

Papers overview

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2013
2013
Chemical Therapeutics Discovery & Preclinical Development Antitumor Activity of a Duocarmycin Analogue Rationalized to Be Metabolically Activated by Cytochrome P 450 1 A 1 in Human Transitional Cell…
We identify cytochrome P450 1A1 (CYP1A1) as a target for tumor-selective drug development in bladder cancer and describe the… 
2012
2012
Antitumor Activity of a Duocarmycin Analogue Rationalized to Be Metabolically Activated by Cytochrome P450 1A1 in Human Transitional Cell Carcinoma of the Bladder
We identify cytochrome P450 1A1 (CYP1A1) as a target for tumor-selective drug development in bladder cancer and describe the… 
2010
2010
Abstract 5424: Combination of decitabine and the tumor-selective CYP450-activated compound ICT2700 produces a synergistic effect in HeLa cells
Over the past decade, much research has been conducted in assessing the role of epigenetics in cancer. Epigenetics refers to… 
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