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ICR1 gene

Known as: H19 ICR, ICR1, H19/IGF2-IMPRINTING CONTROL REGION 
 
National Institutes of Health

Related topics

Related topics

2 relations
Congenital ichthyosis

Narrower (1)

ICR4 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Long non‐coding RNA 91H contributes to the occurrence and progression of esophageal squamous cell carcinoma by inhibiting IGF2 expression
Long non‐coding RNAs (lncRNAs) have been recently recognized as a major class of regulators in mammalian systems. 91H, a novel… Expand
Highly Cited
2014
Highly Cited
2014
Extensive investigation of the IGF2/H19 imprinting control region reveals novel OCT4/SOX2 binding site defects associated with specific methylation patterns in Beckwith-Wiedemann syndrome.
Isolated gain of methylation (GOM) at the IGF2/H19 imprinting control region 1 (ICR1) accounts for about 10% of patients with BWS… Expand
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2014
2014
Methylation analysis in tongue tissue of BWS patients identifies the (EPI)genetic cause in 3 patients with normal methylation levels in blood.
The Beckwith-Wiedemann syndrome is caused by disturbed imprinting of genes at 11p15.5. Routine diagnostic testing for Beckwith… Expand
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Highly Cited
2013
Highly Cited
2013
Beckwith-Wiedemann Syndrome: Growth Pattern and Tumor Risk according to Molecular Mechanism, and Guidelines for Tumor Surveillance
Background: Beckwith-Wiedemann syndrome (BWS) is an overgrowth syndrome associated with an increased risk of pediatric tumors… Expand
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2012
2012
Beckwith Wiedemann imprinting defect found in leucocyte but not buccal DNA in a child born small for gestational age
BackgroundLoss of methylation (LOM) at imprinting control region (ICR) 1 or LOM at ICR 2 on chromosome 11p15 in leucocyte DNA is… Expand
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Highly Cited
2010
Highly Cited
2010
Decreased placental methylation at the H19/IGF2 imprinting control region is associated with normotensive intrauterine growth restriction but not preeclampsia.
UNLABELLED Many genes exhibiting genomic imprinting, parent-of-origin differences in gene expression, are involved in regulating… Expand
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2008
2008
ICR1 Epimutations in 11p15 are Restricted to Patients with Silver-Russell Syndrome Features
(Epi)mutations affecting chromosome llp15 are well known to be associated with growth disturbances. The finding of llp15… Expand
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2008
2008
A novel ROP/RAC GTPase effector integrates plant cell form and pattern formation
ROPs/RACs are the only known signaling Ras superfamily small GTPases in plants. As such they have been suggested to function as… Expand
Highly Cited
2006
Highly Cited
2006
Epigenetic mutations in 11p15 in Silver-Russell syndrome are restricted to the telomeric imprinting domain
Introduction: Silver-Russell syndrome (SRS; also know as Russell-Silver syndrome) is a heterogeneous syndrome which is… Expand
Highly Cited
2006
Highly Cited
2006
IGF-II serum levels are normal in children with Silver-Russell syndrome who frequently carry epimutations at the IGF2 locus.
CONTEXT Epigenetic mutations of 11p15 encompassing IGF2 are present in short children with Silver-Russell syndrome (SRS) with… Expand
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