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ICR1 gene

Known as: H19 ICR, ICR1, H19/IGF2-IMPRINTING CONTROL REGION 
 
National Institutes of Health

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Related topics

2 relations
Congenital ichthyosis

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ICR4 gene

Papers overview

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2016
2016
Kaiso mediates human ICR1 methylation maintenance and H19 transcriptional fine regulation
BackgroundGenomic imprinting evolved in a common ancestor to marsupials and eutherian mammals and ensured the transcription of… Expand
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2015
2015
Long non-coding RNA 91H contributes to the occurrence and progression of esophageal squamous cell carcinoma by inhibiting IGF2 expression.
Long non-coding RNAs (lncRNAs) have been recently recognized as a major class of regulators in mammalian systems. 91H, a novel… Expand
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2015
2015
Reduced DNA methylation at the PEG3 DMR and KvDMR1 loci in children exposed to alcohol in utero: a South African Fetal Alcohol Syndrome cohort study
Fetal alcohol syndrome (FAS) is a devastating developmental disorder resulting from alcohol exposure during fetal development. It… Expand
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2014
2014
Extensive investigation of the IGF2/H19 imprinting control region reveals novel OCT4/SOX2 binding site defects associated with specific methylation patterns in Beckwith-Wiedemann syndrome.
Isolated gain of methylation (GOM) at the IGF2/H19 imprinting control region 1 (ICR1) accounts for about 10% of patients with BWS… Expand
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2014
2014
Methylation analysis in tongue tissue of BWS patients identifies the (EPI)genetic cause in 3 patients with normal methylation levels in blood.
The Beckwith-Wiedemann syndrome is caused by disturbed imprinting of genes at 11p15.5. Routine diagnostic testing for Beckwith… Expand
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Highly Cited
2013
Highly Cited
2013
Beckwith-Wiedemann Syndrome: Growth Pattern and Tumor Risk according to Molecular Mechanism, and Guidelines for Tumor Surveillance
Background: Beckwith-Wiedemann syndrome (BWS) is an overgrowth syndrome associated with an increased risk of pediatric tumors… Expand
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Highly Cited
2010
Highly Cited
2010
Decreased placental methylation at the H19/IGF2 imprinting control region is associated with normotensive intrauterine growth restriction but not preeclampsia.
UNLABELLED Many genes exhibiting genomic imprinting, parent-of-origin differences in gene expression, are involved in regulating… Expand
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2008
2008
ICR1 Epimutations in 11p15 are Restricted to Patients with Silver-Russell Syndrome Features
(Epi)mutations affecting chromosome llp15 are well known to be associated with growth disturbances. The finding of llp15… Expand
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2006
2006
IGF-II serum levels are normal in children with Silver-Russell syndrome who frequently carry epimutations at the IGF2 locus.
CONTEXT Epigenetic mutations of 11p15 encompassing IGF2 are present in short children with Silver-Russell syndrome (SRS) with… Expand
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2005
2005
Epigenetic mutations in 11p15 in Silver-Russell syndrome are restricted to the telomeric imprinting domain.
INTRODUCTION Silver-Russell syndrome (SRS; also know as Russell-Silver syndrome) is a heterogeneous syndrome which is… Expand
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