ICL 670

Known as: ICL670, ICL-670A, ICL670A 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1984-2016
051019842016

Papers overview

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2011
2011
HIV-1 transcription is activated by HIV-1 Tat protein, which recruits cyclin-dependent kinase 9 (CDK9)/cyclin T1 and other host… (More)
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2008
Highly Cited
2008
OBJECTIVES/METHODS This 1-yr prospective phase II trial evaluated the efficacy of deferasirox in regularly transfused patients… (More)
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2007
2007
BACKGROUND Iron chelation therapy (ICT) with deferoxamine (DFO), the current standard for the treatment of iron overload in… (More)
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Highly Cited
2006
Highly Cited
2006
Deferasirox (ICL670) is a once-daily oral iron chelator developed for the treatment of chronic iron overload from blood… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND AND OBJECTIVES Iron accumulation is an inevitable consequence of chronic blood transfusions and results in serious… (More)
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Highly Cited
2006
Highly Cited
2006
Maria Domenica Cappellini, Alan Cohen, Antonio Piga, Mohamed Bejaoui, Silverio Perrotta, Leyla Agaoglu, Yesim Aydinok, Antonis… (More)
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Highly Cited
2005
Highly Cited
2005
The primary targets of iron chelators used for treating transfusional iron overload are prevention of iron ingress into tissues… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Transfusional iron overload is a potentially fatal complication of the treatment of thalassaemia. We aimed to… (More)
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2003
2003
ICL670 is an orally active representative of a new class of tridentate iron chelator developed for the treatment of blood… (More)
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