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ICL 670

Known as: ICL670, ICL-670A, ICL670A 
National Institutes of Health

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Broader (1)

deferasirox

Papers overview

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Review
2008
Review
2008
Long-term experience with deferasirox (ICL670), a once-daily oral iron chelator, in the treatment of transfusional iron overload
Background: Chronic iron overload from frequent blood transfusions to treat patients with severe anaemias leads to significant… 
Highly Cited
2007
Highly Cited
2007
Correction of anemia in a transfusion-dependent patient with primary myelofibrosis receiving iron chelation therapy with deferasirox (Exjade®, ICL670)
Transfusional iron overload in patients with chronic anemias can result in multiple organ failure. Experience in the management… 
2006
2006
Phase II clinical evaluation of deferasirox, a once-daily oral chelating agent, in pediatric patients with beta-thalassemia major.
BACKGROUND AND OBJECTIVES: Deferasirox (ICL670) is a novel once-daily oral iron chelator developed for the treatment of chronic… 
2005
2005
Improved Myocardial T2* in Transfusion Dependent Anemias Receiving ICL670 (Deferasirox).
ICL670 (deferasirox) is an orally active iron chelator, intended as once daily mono-therapy for the treatment of transfusional… 
2005
2005
Iron Chelation Efficiency of Deferasirox (Exjade®, ICL670) in Patients with Transfusional Hemosiderosis.
Iron excretion can be calculated according to Angelucci et al (NEJM 2000). As applied to the novel oral iron chelator deferasirox… 
2005
2005
Transport Kinetics of Iron Chelators and Their Chelates in Caco-2 Cells
PurposeCaco-2 monolayers were used to contrast the bidirectional transport of iron chelators and their chelates and to estimate… 
Review
2004
Review
2004
Iron chelation therapy in sickle-cell disease and other transfusion-dependent anemias.
2002
2002
Posterior chamber phakic intraocular lens for moderate myopia and hyperopia.
BACKGROUND As part of the United States Food and Drug Administration Phase III clinical trial, patients were implanted with the… 
2000
2000
Modification of native collagen reduces antigenicity but preserves cell compatibility
Porcine intestinal collagen (ICL), derived from processed small intestine, is used as a part of a remodelable bilaminate… 
1994
1994
Intracytoplasmic lumina in ependymomas: an ultrastructural study.
Intracytoplasmic lumina (ICL) are rarely described in tumors of the central nervous system. The morphogenesis of ICL remains… 
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